Humoral Control of Growth and Differentiation, Volume I: Vertebrate Regulatory Factors is a part of two-volume work that introduces the reader to humoral control of growth and differentiation in vertebrates. This volume gives emphasis on chemical messengers, which have received relatively little attention in standard treatises on endocrine physiology for a number of reasons.
Organized into three parts, this book begins with the physiological significance of chalones. This class of hormones is intimately associated with mitotic homeostasis as inhibitors of cell division. The book then looks into the aspects of blood cell formation and release, as well as the humoral control of organs and tissue growth. This volume also includes chapters discussing the humoral changes occurring in diseases of the blood and other pathologic states. The humoral factors influencing lymphocyte proliferation in culture are also explained. Moreover, this volume examines the effects of the more orthodox hormones upon skeletal growth and regeneration.