Hyperlipidaemia

Paperback | March 28, 2012

EditorJohn Betteridge

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In the last decade, advances in the understanding of lipoprotein and lipid metabolism have developed enormously. This has resulted in a detailed knowledge of the mechanisms underlying the primary and secondary dyslipidaemias. Furthermore, the role of lipoproteins in atherogenesis isincreasingly understood at the cellular and molecular level. In this book, the scale of the problem of cardiovascular disease (CVD) is described together with the possibilities for prevention. The pathophysiology of lipid and lipoproteins provide a background to the understanding of the primary and secondary dyslipidaemias and the mechanism of action of thedifferent drug classes.A practical approach to therapy is provided including diet, lifestyle, and therapeutic approaches. Common clinical problems are addressed and the book looks to the future, principally in relation to new therapeutic targets. This book provides the basis for the translation of clinical trial scienceinto everyday clinical practice for the benefit of the individual patient.

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In the last decade, advances in the understanding of lipoprotein and lipid metabolism have developed enormously. This has resulted in a detailed knowledge of the mechanisms underlying the primary and secondary dyslipidaemias. Furthermore, the role of lipoproteins in atherogenesis isincreasingly understood at the cellular and molecular ...

John Betteridge is Professor of Endocrinology and Metabolism at University College, London, UK.

other books by John Betteridge

Format:PaperbackDimensions:160 pages, 7.09 × 3.94 × 0.07 inPublished:March 28, 2012Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:019954350X

ISBN - 13:9780199543502

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Table of Contents

1. Professor Guy De Backer: Epidemiology of cardiovascular disease: the scale of the problem2. Joanna Gouni-Berthold and Wilhelm Krone: Lipids, lipoproteins and atherogenesis3. Catherine McGorrian, Tora Leong, Ralph D'Agostino, Marie-Therese Coney and Ian M. Graham: Risk estimation systems in clinical use: SCORE, HeartScore, Framingham, PROCAM, ASSIGN and QRISK4. Anton F. H. Stalenhoef: Primary dyslipidaemias5. Rafael Carmena and Jose T Real: Secondary dyslipidemias6. Jonathan Morrell and Jacqueline Morrell: Diet and lifestyle7. D. John Betteridge: Pharmacological therapy: Statins8. D. John Betteridge: Pharmacological therapy: Non-Statin Drugs9. Anthony S. Wierzbicki: Combination therapy for the management of hyperlipidaemia10. D. John Betteridge: Recent lipid-lowering trials in perspective: Implications for therapy11. Manish Kalla and Julian Halcox: Vascular imaging12. John Reckless: Common problems in lipid management