Immunology

Paperback | August 5, 2011

byRaj Khanna

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The early chapters of the book provide a broad overview of the immune system and its functioning. The subsequent chapters present the importance of discriminating self from non-self through pattern recognition receptors (PRRs), structure and function of antibodies, major histocompatabilitycomplex, antigen receptors of the adaptive immune system, cellular interactions that lead to activation of T and B lymphocytes, immune responses against various categories of pathogens, and manipulation of the immune system by vaccination and various vaccine strategies. The book also includesclinically significant areas and hypersensitivity states including allergy, immunodeficiency disorders, transplantation, and tumor immunology. There is also a special emphasis on the HIV/AIDS pandemic against which efforts are on at a massive scale. Tolerance and autoimmunity have also been linkedfor a better understanding of the mechanisms that could lead to autoimmune diseases.An additional feature of the book is the inclusion of various techniques, immunoassays, and experimental systems provided in the appendix. ELISA and other immunological techniques like agglutination and precipitation having wide ranging applications have also been included in the book.

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The early chapters of the book provide a broad overview of the immune system and its functioning. The subsequent chapters present the importance of discriminating self from non-self through pattern recognition receptors (PRRs), structure and function of antibodies, major histocompatabilitycomplex, antigen receptors of the adaptive immu...

Raj Khanna, a gold medallist in Biochemistry, obtained her master's and doctoral degrees from Lucknow University. She recently retired as Professor of Biochemistry, University of Lucknow, and is now actively engaged in book writing. Her research work has centered on the area of clinical biochemistry and she has been associated with var...
Format:PaperbackDimensions:464 pagesPublished:August 5, 2011Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0198068263

ISBN - 13:9780198068266

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Table of Contents

PrefaceIcons used in illustrationsThe immune system - an overview1. The immune system- an introduction2. Innate immune response to infections3. The lymphoid system and cells of adaptive immunity4. Antigens and antibodies5. Major histocompatability complex (MHC)6. Generation of antibody diversity and B lymphocyte development7. Cytokines8. T lymphocyte maturation and activation9. Effector mechanisms of cell-mediated immunity10. Activation of B lymphocytes11. Effector mechanisms of humoral immunity12. Immune response against microbes13. Vaccination and vaccine strategies14. Hypersensitivity reactions15. Immunologic tolerance and autoimmunity16. Immunodeficiency diseases17. Transplantation and graft rejection18. Tumor immunologyAppendix A Immunological techniques: principles and applicationsAppendix B Cumulative glossaryFurther readingIndex