Immunotoxicology and Risk Assessment by Dennis K. FlahertyImmunotoxicology and Risk Assessment by Dennis K. Flaherty

Immunotoxicology and Risk Assessment

byDennis K. Flaherty

Hardcover | May 31, 1999

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This authored book presents basic immunological tenets and mechanisms at the cellular and molecular level while employing the toxicology focus on hazard identification, appropriate assays, dose response, and risk assesment by mathematical models and safety factors. It will be a useful reference to toxicologists because it will incorporate new guidelines that the EPA is bringing out later this year for all chemicals regulated under the Federal Insecticide, Fungicide, and Rodenticide Act and the Toxic Substances Control Act. Regulatory sections in each chapter focus on data from both the US Food and Drug Administration, as well as data applicable to western European Nations.
Title:Immunotoxicology and Risk AssessmentFormat:HardcoverDimensions:382 pagesPublished:May 31, 1999Publisher:Kluwer Boston Inc.Language:English

The following ISBNs are associated with this title:

ISBN - 10:030645971X

ISBN - 13:9780306459719

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Table of Contents

to Immunotoxicology.- Innate Immunity.- Cells of the Immune System.- Immunogenicity and Antigenicity.- Antigen-Presenting Cells.- Antigen Presentation.- Surface Interactions and Intracellular Signaling.- B-Cell Activation.- Antibodies.- Immunological Memory.- Complement.- Phagocytosis and Intracellular Killing.- Immediate Hypersensitivity Reactions.- Autoimmunity.- Delayed Hypersensitivity Reactions.- Killer Cells.- Killer Cells and Viral Infections.- Transplantation.- The Kines.- Assessment of Biological Significance.- Risk Characterization.- References.