Inflammation and Cancer: Methods and Protocols: Volume 1, Experimental Models and Practical Approaches by Serguei V. KozlovInflammation and Cancer: Methods and Protocols: Volume 1, Experimental Models and Practical Approaches by Serguei V. Kozlov

Inflammation and Cancer: Methods and Protocols: Volume 1, Experimental Models and Practical…

EditorSerguei V. Kozlov

Paperback | November 19, 2010

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According to the most recent clinical oncology data, one out of seven newly diagnosed malignancies worldwide result from infection and chronic inflammation in conjunction with cancer. In Inflammation and Cancer: Methods and Protocols, expert researchers deliver a systematic guide to techniques addressing various aspects of experimental cancer biology, selectively focused on inflammation-mediated tumorigenesis, while promoting improvisations on a per-case basis. Volume 1, Experimental Models and Practical Approaches provides an overview of a spectrum of techniques developed to analyze the outcomes of inflammation-mediated carcinogenesis on the tissue, cellular, and molecular levels while highlighting several diagnostic aspects, such as biomarker discovery and molecular signatures evaluation. Written in the highly successful Methods in Molecular BiologyT series format, chapters include brief introductions to their subjects, lists of the necessary materials and reagents, step-by-step laboratory protocols, and a notes section, which examines tips on troubleshooting and avoiding known pitfalls.Comprehensive and cutting-edge, Inflammation and Cancer: Methods and Protocols promises to serve as a vital guide and resource for investigators and clinicians working toward the goal of combatting the estimated 2, 200 inflammation-related oncogenesis fatalities occurring every day.
Title:Inflammation and Cancer: Methods and Protocols: Volume 1, Experimental Models and Practical…Format:PaperbackDimensions:392 pages, 10.24 × 7.6 × 0.01 inPublished:November 19, 2010Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617379239

ISBN - 13:9781617379239


Table of Contents

Part I: Experimental Approaches to Study Chronic Inflammation-Related Carcinogenesis1. Collection and Preparation of Rodent Tissue Samples for Histo-Pathological and Molecular Studies in CarcinogenesisYelena Golubeva and Keith Rogers2. Biomarkers of Cell Proliferation in Carcinomas: Detection of Angiogenesis and Infiltrated LeukocytesCoen I.M. Baeten3. Assessment of Local Proteolytic Milieu as a Factor in Tumor Invasiveness and Metastasis Formation: In vitro Collagen Degradation and Invasion AssaysBrenda L. Petrella4. Cytokine Multiplex AnalysisHoward A. Young5. Approaches to Determine Expression of Inflammatory CytokinesDerk Amsen, Karin E. de Visser, and Terrence Town6. Selective Immortalization of Tumor-Specific T Cells to Establish Long-Term T Cell Lines Maintaining Primary Cell CharacteristicsEugene V. Barsov7. YKL-40: A Novel Marker Shared by Chronic Inflammation and Oncogenic TransformationAnne Roslind and Julia S. Johansen8. Angiogenesis Links Chronic Inflammation with CancerHanako Kobayashi and P. Charles Lin9. Inflammatory Bowel Disease: A Model of Chronic Inflammation-Induced CancerGuang-Yu Yang, Sofia Taboada, and Jie Liao Part II: Oncogenic Potential of Inflammation Induced by Viral and Bacterial Infections10. Gastric Carcinogenesis and Helicobacter pylori InfectionChristine Varone, Jean-François Mosnier, Philippe Lehours, Tamara Matysiak-Budnik, and Francis Mégraud11. Helicobacter-Based Mouse Models of Digestive System CarcinogenesisArlin B. Rogers and JeanMarie Houghton12. Screening for Molecular Markers of Cervical Papillomavirus Infection: Overview of Methods and Their Clinical ImplicationsDonna Dehn, Adriann Taylor, Timothy J. Fischer, Douglas P. Malinowski, and Kenneth R. Shroyer13. Screening for Epstein-Barr Virus in Hodgkin's LymphomaGulfaraz Khan14. A Hepatitis C Virus Xenograft Mouse Efficacy ModelQing Zhu and Amy J. Weiner15. Gene Expression Profiling in Cervical Cancer: Identification of Novel Markers for Disease Diagnosis and TherapyCara M. Martin, Katharine Astbury, Lynda McEvoy, Sharon O'Toole, Orla Sheils, and John J. O'Leary16. Detection and Genotyping Analysis of Human Papillomavirus Isolates from Liquid-Based Cervical Cytology SpecimensPatricia Avissar and Douglas P. Malinowski