Innate Immunity by Jonathan EwbankInnate Immunity by Jonathan Ewbank

Innate Immunity

EditorJonathan Ewbank, Eric Vivier

Paperback | December 10, 2010

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This volume contains chapters dealing with the isolation and functional characterization of cells involved in innate immunity in mouse and man, including mast cells and eosinophils, and with several chapters focusing on natural killer cells. These approaches and models are being used to dissect the complex interplay between hosts and pathogens, and contribute to developing strategies to help fight infection.

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Title:Innate ImmunityFormat:PaperbackDimensions:472 pages, 9.02 × 5.98 × 0.68 inPublished:December 10, 2010Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617377546

ISBN - 13:9781617377549

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Table of Contents

ENU mutagenesis in miceInnate immunity genes as candidate genes: searching for relevant natural polymorphisms in databases and assessing family-based association of polymorphisms with human diseasesKIR locus polymorphisms: Genotyping and disease association analysisExperimental model for the study of the human immune system: production and monitoring of "Human Immune System" Rag2-/-gc-/- miceBAC transgenesis via pronuclear injection of fertilised mouse oocytesBioluminescence Imaging to Evaluate Infections and Host Response In VivoIntravital Two photon Imaging of Natural Killer Cells and Dendritic Cells in Lymph NodesDissection of the antiviral NK cell response by MCMV mutantsAnalyzing antibody-Fc-receptor interactionsThe isolation and identification of murine dendritic cell populations from lymphoid tissues and their production in culture.Analysis of Individual Natural Killer Cell ResponsesIsolation and Analysis of Human Natural Killer Cell SubsetsInnate immune function of eosinophils: from anti-parasite to anti-tumor cellsEx vivo and in vitro Primary Mast CellsMurine Macrophages: a technical approach.Clinical analysis of dendritic cell subsets: the dendritogramClinical analysis of human NK cellsLentiviral transduction of immune cellsAxenic mice modelIn vivo analysis of Zebrafish innate immunityReverse genetics analysis of antiparasitic responses in the malaria vector, Anopheles gambiae.Drosophila Immunity : Methods for Monitoring the Activity of Toll and Imd Signaling Pathways.Investigating the involvement of host factors involved in intracellular pathogen infection by RNAi in Drosophila cellsModels of Caenorhabditis elegans Infection by Bacterial and Fungal PathogensGenetic analysis of C. elegans innate immunity Measuring Cell Wall-Based Defenses and Their Effect on Bacterial Growth in Arabidopsis

Editorial Reviews

From the reviews:"The methods described in this book include step-by-step protocols to isolate cells that are involved in the innate immune response as well as a variety of other methods that could be useful. . The book is written for laboratory researchers . . It offers a detailed description of the reagents and procedures that are used for each of the protocols and could be used by immunologists, histologists, geneticists, and cell biologists. . an excellent addition to any laboratory which could use these techniques." (Marion C. Cohen, Doody's Review Service, December, 2008)