Insulin-like Growth Factor Receptor Signalling

Hardcover | July 31, 2003

EditorDerek Leroith, Walter Zumkeller, Robert C. Baxter

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Insulin-like growth factors are ubiquitously expressed and are crucial for growth and function of almost all cells. Together with their binding proteins and receptors, they form a widely studied biological system involving many proteins and characterized by complex interactions. In addition to its significance in growth and development, the insulin-like growth factor system also has important roles in a wide variety of pathological states. This has led to interest in the therapeutic potential of insulin-like growth factors and their binding proteins as candidate drug targets. This comprehensive book contains current information on both basic science and clinical aspects of IGFs and their regulatory proteins, with emphasis on their relevance to cancer.

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Insulin-like growth factors are ubiquitously expressed and are crucial for growth and function of almost all cells. Together with their binding proteins and receptors, they form a widely studied biological system involving many proteins and characterized by complex interactions. In addition to its significance in growth and development...

Format:HardcoverDimensions:516 pages, 9.25 × 6.1 × 0 inPublished:July 31, 2003Publisher:Springer USLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0306478463

ISBN - 13:9780306478468

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"A timely and useful book with references, tables and good quality figures. Highly recommended to all endocrinologists, diabetologists, oncologists, neurologists, physiologists, biologists and pediatricians who want a better understanding of growth." (Journal of Pediatric Endocrinology & Metabolism, 16:9 (2003)