Insulin Resistance and Polycystic Ovarian Syndrome: Pathogenesis, Evaluation, and Treatment by Evanthia Diamanti-KandarakisInsulin Resistance and Polycystic Ovarian Syndrome: Pathogenesis, Evaluation, and Treatment by Evanthia Diamanti-Kandarakis

Insulin Resistance and Polycystic Ovarian Syndrome: Pathogenesis, Evaluation, and Treatment

EditorEvanthia Diamanti-Kandarakis

Paperback | November 9, 2010

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Polycystic Ovarian Syndrome (PCOS) is the most common endocrinopathy in women of reproductive age. Providing a state-of-the-art analysis of the connection between insulin resistance and PCOS, this book comprehensively covers a range of topics. It provides an up-to-date and balanced overview of PCOS, with specific attention to the role of insulin resistance in its pathogenesis. It also examines diet and lifestyle factors in the aetiology and management of PCOS.
Title:Insulin Resistance and Polycystic Ovarian Syndrome: Pathogenesis, Evaluation, and TreatmentFormat:PaperbackDimensions:491 pages, 10 × 7.01 × 0 inPublished:November 9, 2010Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617377635

ISBN - 13:9781617377631

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Table of Contents

1. EVALUATION FOR INSULIN RESISTANCE AND CO-MORBIDITIES RELATED TOINSULIN RESISTANCE IN PCOSRicardo Azziz, MD, MPH, MBADept. of Ob/Gyn, Cedars-Sinai Medical Center, and Depts. of Ob/Gyn andMedicine, The David Geffen School of Medicine at UCLA, Los Angeles, CA,USA2. FAT DISTRIBUTION AND ADIPOSE PRODUCTS IN PCOSRunning title: Adipose products in PCOSEnrico Carmina, M.D.Department of Clinical Medicine, University of Palermo, Palermo, Italy3. Treatment of Infertility in PCOS: Ovulation InductionRunning head: Ovulation Induction in PCOSAuthors: Deborah S. Wachs, MDUniversity of California, San DiegoSchool of MedicineDepartment of Reproduction Medicine*R. Jeffery Chang, MDUniversity of California, San DiegoSchool of MedicineDepartment of Reproduction Medicine4. IMAGING STUDIES IN POLYCYSTIC OVARY SYNDROMESophie JONARD, MD 1, Yann ROBERT, MD 2, Yves ARDAENS, MD 2 and DidierDEWAILLY, MD 11 Department of Endocrine Gynaecology and Reproductive Medecine,Hopital Jeanne de Flandre, Centre Hospitalier et Universitaire deLille, France2 Department of Radiology, Hopital Jeanne de Flandre, CentreHospitalier et Universitaire de Lille, France5. GENES RELATED TO METABOLIC ABNORMALITIES OR INSULIN RESISTANCE INPCOSSHORT TITLE: Insulin resistance genes in PCOSHéctor F. Escobar-Morreale, MD, PhDDepartment of Endocrinology, Hospital Ramón y Cajal & Department ofMedicine, Universidad de Alcalá, Madrid, Spain6. ANTI-ANDROGENSKür_ad Ünlühizarci, M.D. and Fahrettin Kele_timur, M.D.Department of Endocrinology, Erciyes University Medical School,Kayseri, Turkey7. LIPID ABNORMALITIES IN PCOSAbbreviated title: Lipids and PCOSDjuro Macut, M.D., PhD.Institute of Endocrinology, Diabetes and Diseases of Metabolism, DrSubotica 13, 11000 Belgrade, Serbia8. Serine Phosphorylation, Insulin Resistance, and the Regulation OFANDROGEN SYNTHESISRunning title: Serine phosphorylation, insulin resistance, andsteroidogenesisAndrew A. Bremer M.D., Ph.D.*, Walter L. Miller, M.D.Department of Pediatrics, University of California, San Francisco*Supported by Pediatric Endocrinology Training Grant T32 DK071619. CHRONIC TREATMENT OF POLYCYSTIC OVARIAN SYNDROME:ORAL CONTRACEPTIVE PILLSRunning Title: PCOS and OCP treatmentShahla Nader, M.D.Departments of Obstetrics, Gynecology & Reproductive Sciences andInternal MedicineThe University of Texas Medical School - Houston10. INSULIN SENSITIZING DRUGS FOR THE TREATMENT OF INFERTILITY INPOLYCYSTIC OVARY SYNDROME(Insulin Sensitizing Drugs in PCOS)Cynthia S. Ryan, MDa, John E. Nestler, MDbcaClinical Fellow, Division of Endocrinology and Metabolism, MedicalCollege of Virginia, Virginia Commonwealth University, Richmond,VirginiabWilliam G. Blackard Professor of Medicine and Chair, Division ofEndocrinology and Metabolism, Medical College of Virginia, VirginiaCommonwealth University; and cVice Chair Department of InternalMedicine, Medical College of Virginia, Virginia CommonwealthUniversity, Richmond, Virginia11. DIET AND LIFESTYLE FACTORS IN THE AETIOLOGY AND MANAGEMENT OFPOLYCYSTIC OVARY SYNDROMER. J. NORMAN1 and L.J. MORAN21Research Centre for Reproductive Health and Repromed,The Queen Elizabeth HospitalUniversity of AdelaideSouth Australia, Australia2CSIRO Human Nutrition,Kintore Avenue, Adelaide 5000South Australia, Australia12. ADRENARCHE: THE INTERRELATIONSHIP OF ANDROGENS/ INSULIN ON THEDEVELOPMENT OF THE METABOLIC SYNDROME/ PCOSRunning Head: Adrenarche: Metabolic Syndrome/ PCOSAuthors: Sharon E. Oberfield, M.D(1), Natasha Leibel, M.D. (1), LaurenAntler B.A. (1), Miriam Silfen, M.D. (1), Lenore S. Levine, M.D. (1),Mary Horlick, M.D. (1), Goldy Carbunaru M.D.(2), Ximena Lopez, M.D.(2)and Songya Pang M.D. (2)Institution: (1) Morgan Stanley's Children's Hospital of NewYork-Presbyterian (NY, NY)(2) University of Illinois Hospital, Department of Pediatrics(Chicago, IL)13. Cardiovascular disease and inflammationRunning head : PCOS and CVDFrancesco Orio1, Evanthia Diamanti-Kandarakis2, Stefano Palomba31 Department of Molecular and Clinical Endocrinology & Oncology,University "Federico II", Naples, Italy2 Endocrine Section of First Department of Internal Medicine, AthensUniversity School of Medicine, Athens, Greece3 Department of Obstetrics and Gynecology, University "Magna Graecia",Catanzaro, Italy14. Surgery and laser diathermyStefano Palomba*, Fulvio Zullo*, Evanthia Diamanti-Kandarakis^,Francesco Orio Jr°*Department of Obstetrics & Gynecology, University "Magna Graecia" ofCatanzaro°Department of Endocrinology and Molecular Oncology, University"Federico II" of Naples, Italy^Endocrine Section, First Department of Medicine, University of Athens,Greece15. Late pregnancy complications in polycystic ovarian syndromeShort running title: Late pregnancy complications in PCOSDimitrios Panidis1, Neoklis A. Georgopoulos21 Professor of EndocrinologyDivision of Endocrinology and Human Reproduction, Second Department ofObstetrics and Gynaecology, Aristotle University of Thessaloniki,Thessaloniki, Greece2 Lecturer of Reproductive EndocrinologyDepartment of Obstetrics and Gynaecology, Division of ReproductiveEndocrinology, Patras Medical School, Patras, Greece16. Glucose intoleranceRunning head: Glucose intoleranceVincenzo ToscanoDipartimento di Fisiopatologia Medica - University of Rome La SapienzaII Facoltà di Medicina e Chirurgia17. HORMONAL AND BIOCHEMICAL EVALUATION OF POLYCYSTIC OVARY SYNDROMEBulent O. Yildiz, M.D.Hacettepe University Faculty of Medicine, Department of InternalMedicine, Endocrinology and Metabolism Unit, Ankara, Turkey, 0610018. ENDOMETRIAL CARCINOMA IN PCOSEmmanuel DiakomanolisAlexandra Hospital, Athens Greece19. STATINS, OXIDATIVE STRESS, AND PCOSPinar H. Kodaman and Antoni J. DulebaYale University School of MedicineDepartment of Obstetrics/GynecologyNew Haven, CT O652020. GLUCOSE INTOLERANCE IN PCOS: FOCUS ON THE ß-CELLRunning Title: Diabetes in PCOSDavid A. Ehrmann, M.D.Department of Medicine, University of Chicago, Chicago, IL.21. PCOS: definitions and epidemiologyBart C.J.M. Fauser1Frank J. Broekmans1Joop S.E. Laven2Nick S. Macklon1Basil Tarlatzis31 Department of Reproductive Medicine & Gynecology,University Medical Center, Heidelberglaan 100, 3584 CX Utrecht, TheNetherlandsE mail; b.c.fauser@umcutrecht.nl2 Center of Reproductive MedicineErasmus Medical Center, Rotterdam, The Netherlands3 Unit for Human Reproduction, 1st Department of Obstetrics &Gynecology, Aristotle University of Thessaliniki, Greece22. ANOVULATION IN POLYCYSTIC OVARY SYNDROMEStephen FranksInstitute of Reproductive and Developmental Biology, Wolfson and WestonResearch Centre for Family Health, Imperial College London, HammersmithHospital, London, W12 0NN, UK23. NON-ALCOHOL_C FATTY L_VER D_SEASE _N PCOSWalter Futterweit, M.D., F.A.C.P. *Clinical Professor of Medicine, Division of Endocrinology, Mount SinaiSchool of Medicine, New York, N.Y., 1002924. "SECONDARY" POLYCYSTIC OVARY SYNDROMEGregory Kaltsas1 & George Chrousos2The Department of Pathophysiology1 & the First Department ofPaediatrics2, Athens University Medical School, Athens, Greece25. LONG TERM SEQUELAE OF POLYCYSTIC OVARY SYNDROME: ASSOCIATION WITHINSULIN RESISTANCE AND THE METABOLIC SYNDROMERichard S. Legro, M.D.,Professor, Department of Obstetrics and Gynecology, Pennsylvania StateUniversity College of Medicine, Hershey, PA26. THE INSULIN RESISTANCE OF POLYCYSTIC OVARY SYNDROMEShort title: The insulin resistance of PCOSMerik Demissie Ph.D.1, Richard S. Legro, M.D. 2, Andrea Dunaif, M.D. 11 The Division of Endocrinology and Molecular Medicine, The FeinbergSchool of Medicine, Northwestern University, Chicago, USA2 The Department of Obstetrics and Gynecology, Pennsylvania StateUniversity, Hershey, PA, USA27. THERAPEUTIC ASPECTS OF POLYCYSTIC OVARY SYNDROME IN ADOLESCENCEGeorge MASTORAKOS, Carolina KOLIOPOULOS, George CREATSASEndocrine Unit, 2nd Department of Obstetrics and Gynecology, ARETAIEIONHospital, Medical School of CAPODISTRIAKON Athens University28. Lifestyle intervention in PCOSRunning head: Lifestyle intervention in PCOSOnno E. Janssen, M.D., Susanne Tan, M.D. and Susanne Hahn, M.D.Div. of Endocrinology, Dept. of Medicine, University Hospital of EssenMedical School, Hufelandstrasse 55, 45122 Essen, Germany29. INVOLVEMENT OF THE ENDOCANNABINOID SYSTEM IN METABOLISM ANDFERTILITY: POTENTIAL IMPLICATION IN THE POLYCYSTIC OVARY SYNDROMEUberto Pagotto, Alessandra Gambineri, Valentina Vicennati, and RenatoPasqualiEndocrinology Unit, Department of Internal Medicine and Gastroenterologyand C.R.B.A., S.Orsola-Malpighi Hospital, Alma Mater StudiorumUniversity of Bologna, 40138 Bologna, Italy.30. Insulin resistance: definition and epidemiology in normal womenand PCOS women.Renato Pasquali and Alessandra GambineriEndocrinology Unit, Dept. of Internal Medicine, S. Orsola-MalpighiHospital, University of Bologna, Italy.31. Clinical evaluation of Polycystic Ovary SyndromeAnn E. Taylor, MDPfizer Global Research and Development, Groton, CT 06340, United States32. PHARMACEUTICAL INTERVENTION IN METABOLIC AND CARDIOVASCULAR RISKFACTORS IN PCOSEvanthia Diamanti-Kandarakis, MDAssociate Professor, Medical School, University of Athens, Greece33. INSULIN RESISTANCE AND EARLY PREGNANCY LOSS IN POLYCYSTIC OVARYSYNDROMEDaniela Jakubowicz1, MD and Susmeeta T. Sharma2, MBBS1 Division of Reproductive Endocrinology. Department of MedicineHospital de Clinicas Caracas, Venezuela.2 Division of Endocrinology & Metabolism, Virginia CommonwealthUniversity, Richmond, Virginia, USA.

Editorial Reviews

From the reviews:"This volume provides an up to date comprehensive review on various aspects of the polycystic ovary syndrome (PCOS), a more and more diagnosed disorder also in adolescent girls. It is divided into 6 parts . . A well written and informative text." (Pediatric Endocrinology Reviews, Vol. 5 (3), 2008)"This is an overview of the association between insulin resistance and polycystic ovary syndrome (PCOS) with a special focus on pathogenesis, evaluation, and treatment. The book also focuses on the other metabolic and fertility issues occurring in PCOS. . Although it can be used by students and residents, it is written primarily for practitioners whose focus is either in endocrinology or obstetrics/gynecology. . The book is useful and the information is current and relevant." (Monica Mortensen, Doody's Review Service, August, 2007)