A lucid and comprehensive review of recent developments made in the understanding of cellular activation phenomena in striated muscle. Basic physical, mathematical, and physiological principles are covered to a more coherent level than currently available in published literature. The phenomenaof intramembrane change is surveyed through a range of biological systems, followed by more detailed analyses of steady-state and kinetic properties, and their relationship to possible underlying physical mechanisms. The book consistently draws correlations both with cellular and molecularbiological information and their physiological consequences and significance. Accessible both as a survey of basic concepts and as an authoritative review of recent work in the field.