Introduction to Glycobiology

Paperback | April 21, 2011

byMaureen E. Taylor, Kurt Drickamer

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Sugars are familiar as vital sources of energy. Yet the biological importance of the sugars extends well beyond their value as cellular fuels.Introduction to Glycobiology reveals the true impact of the sugars on biological systems, explaining their function at the molecular, cellular, and organismal level. Employing a two-part structure, the book leads us through essential principles and concepts upon which the discipline is grounded,before exploring the diverse roles of sugars throughout biological systems, including development, cell signalling, and protein trafficking. It also emphasises the importance of glycobiology in disease, and explains how an understanding of the link between the two is enabling us to develop newtherapeutic strategies.Taking the student from the fundamental principles to the frontiers of the subject, and with a wealth of learning features to get the most out of their studies, Introduction to Glycobiology remains the ideal resource for students and teachers alike.Online Resource CentreFor students:* Updates - surveys of key developments in the field, provided on a six-monthly basis, to maintain currency* Library of molecular structures to help students visualize structures and gain a proper appreciation of the link between structure and function* Hyperlinked references to facilitate access to primary literatureFor registered adopters of the book:* Full colour figures, available for download individually or as PowerPoint slides with key explanatory points* Answers to end of chapter questions* Journal Clubs

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From the Publisher

Sugars are familiar as vital sources of energy. Yet the biological importance of the sugars extends well beyond their value as cellular fuels.Introduction to Glycobiology reveals the true impact of the sugars on biological systems, explaining their function at the molecular, cellular, and organismal level. Employing a two-part structur...

Maureen Taylor is Senior Lecturer in Molecular Biosciences at Imperial College London and Fellow and Tutor in biochemistry at Exeter College, Oxford. Kurt Drickamer is Professor of Biochemistry in the Division of Molecular Biosciences at Imperial College London

other books by Maureen E. Taylor

Format:PaperbackDimensions:320 pages, 9.69 × 7.44 × 0.01 inPublished:April 21, 2011Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199569118

ISBN - 13:9780199569113

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Table of Contents

Part 1: Structures and biosynthesis of glycans1. Concepts of glycobiology2. N-Linked glycosylation3. O-Linked glycosylation4. Glycolipids and membrane protein glycosylation5. Enzymology and cell biology of glycosylation6. Glycomics: analysis of glycan structures7. Conformations of oligosaccharidesPart 2: Glycans in biology8. Effects of glycosylation on protein structure and function9. Carbohydrate recognition in cell adhesion and signalling10. Glycoprotein trafficking in cells and organisms11. Glycobiology of plants, bacteria, and viruses12. Glycobiology and development13. Glycosylation and disease14. The future of glycobiology

Editorial Reviews

"Dr Taylor and Professor Drickamer should be congratulated on writing a textbook that presents the enormous subject of glycobiology with energy and enthusiasm and doing so in a manner that should be accessible to their target audience." --Biochemist e-volution, April 2006