Introduction to the Cellular and Molecular Biology of Cancer

Paperback | July 28, 2005

EditorMargaret Knowles, Peter Selby

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This new edition of Introduction to the Cellular and Molecular Biology of Cancer provides a comprehensive overview of cancer biology, covering the current status of both research and treatment. For the student or new researcher the breadth of cancer research can appear daunting, yet a broadunderstanding is essential for translation of laboratory findings into the clinic. Within the broad scope of the book, each topic is reviewed authoritatively by experts in the field, and the accompanying bibliographies allow rapid access to the relevant current literature. The book covers topics extending from the molecular alterations found in cancer cells and their causes tothe current range of approaches to treatment. Since the publication of the previous edition in 1997 there has been unprecedented progress in cancer research: this is reflected by an extensive revision of all the material, and the addition of eight new chapters, covering DNA repair, epigeneticevents, the cell cycle, cell immortalisation, apoptosis, angiogenesis, animal models, the genome, transcriptome and proteome, radiotherapy and molecular radiotherapy, immunotherapy, and gene therapy. The fourth edition of this popular book will serve as a text for both undergraduate and postgraduate use and also as an introduction for clinicians and scientists new to the field.

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This new edition of Introduction to the Cellular and Molecular Biology of Cancer provides a comprehensive overview of cancer biology, covering the current status of both research and treatment. For the student or new researcher the breadth of cancer research can appear daunting, yet a broadunderstanding is essential for translation of ...

Margaret Knowles is Professor of Experimental Cancer Research at the University of Leeds, and Associate Director of the Cancer Research UK Clinical Centre, also in Leeds. Peter Selby is Professor of Cancer Medicine and Director of the National Cancer Research Network at the University of Leeds.
Format:PaperbackDimensions:552 pages, 9.69 × 7.44 × 1.15 inPublished:July 28, 2005Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:019852563X

ISBN - 13:9780198525639

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Table of Contents

1. L.M. Franks and Margaret A. Knowles: What is cancer?2. Naomi Allen, Robert Newton, Amy Berrington de Gonzalez, Jane Green, Emily Banks, and Timothy J. Key: The causes of cancer3. D. Timothy Bishop: Inherited susceptibility to cancer4. Beate Koberle, John P. Wittschieben, and Richard D. Wood: DNA repair and cancer5. Jonathan C. Cheng and Peter A. Jones: Epigenetic events in cancer6. Denise Sheer and Janet Shipley: Molecular cytogenetics of cancer7. Margaret A. Knowles: Oncogenes8. Sonia Lain and David P. Lane: Tumour suppressor genes9. Chris J. Norbury: The cancer cell cycle10. Robert F. Newbold: Cellular immortalization and telomerase activation in cancer11. Sally A. Prigent: Growth factors and their signalling pathways in cancer12. Dean A. Fennell: Apoptosis: molecular physiology and significance for cancer therapeutics13. Paul Farrell: Mechanisms of viral carcinogenesis14. Peter W. Szlosarek and Frances R. Balkwill: Cytokines and cancer15. Charlotte L. Bevan: Hormones and cancer16. Ian Hart: The spread of tumours17. K.Tahtis and R.Bicknell: Angiogenesis18. Mel Greaves: Stem cells, heamopoiesis, and leukaemia19. Jos Jonkers and Anton Berns: Animal models of cancer20. Peter C. L. Beverley: The immunology of cancer21. Tatjana Crnogorac-Jurcevic, Richard Poulsom, and Nicholas R. Lemoine: The molecular pathology of cancer22. Silvana Debernardi, Rachel Craven, Bryan D. Young, and Rosamonde E. Banks: From transcriptome to proteome23. Ian S. Fentiman: Local treatment of cancer24. D.R. Camidge and D.I. Jodrell: Chemotherapy25. Anne Kiltie: Radiotherapy and molecular radiotherapy26. T. Geldart, M.J. Glennie, and P.W.M. Johnson: Monoclonal antibodies and therapy27. Andrew M. Jackson and Joanne Porte: Immunotherapy of cancer28. John David Chester: Cancer gene therapy29. Peter Sasieni and Jack Cuzick: Screening30. Peter Selby and Margaret A Knowles: Conclusions and prospects

Editorial Reviews

`This is a superb introduction to cancer studies for clinicians and is difficult to fault ... this must be a bargain hard to beat. I strongly recommend this text for all involved in cancer studies and the care of patients with cancer.'Crispian Scully, Oral Oncology