Key Chiral Auxiliary Applications

Hardcover | April 7, 2014

byGregory RoosEditorGregory Roos

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Key Chiral Auxiliary Applications, Second Edition is a detailed compilation of chiral auxiliary applications organized by type of transformation. Continuing from the most important and relevant auxiliaries described in its predecessor, the three-volume set Compendium of Chiral Auxiliary Applications 2001 , as well as advances in the field, the book provides a vital and timely resource for chemists in the field. Each reaction class includes a series of tables and graphical abstracts of real reactions from the literature and patents to enable easy review and comparison of results. This anticipated edition is based on a screening of nearly 40,000 auxiliary reaction applications, with details supplied for the more than 13,000 selected representative entries: synthetic route, reagents, yields, diastereomeric/enantiomeric excesses, and characterization data. Updated and streamlined with more than 60% new material, Key Chiral Auxiliary Applications provides valuable guidance and reliable content for selecting the best auxiliary for a specific asymmetric synthetic transformation. Provides a comprehensive compilation based on nearly 40,000 diverse applications of chiral auxiliaries for selecting the best synthetic route to optically pure compounds Contains over 60% new material with 13,000+ auxiliary applications categorized by reaction type, with reaction details and chemical and optical yields in one unique resource

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From the Publisher

Key Chiral Auxiliary Applications, Second Edition is a detailed compilation of chiral auxiliary applications organized by type of transformation. Continuing from the most important and relevant auxiliaries described in its predecessor, the three-volume set Compendium of Chiral Auxiliary Applications 2001 , as well as advances in the fi...

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Key Chiral Auxiliary Applications, Second Editionis a detailed compilation of chiral auxiliary applications organized by type of transformation. Containing the most important and relevant auxiliaries described in its predecessor, the three-volume setCompendium of Chiral Auxiliary Applications(2001), as well as advances in the field, th...

Greg Roos formal education comprised of a BSc (1971), BSc Honours (1972), and PhD in Organic Synthesis (1976) from the University of Cape Town. A postdoctoral fellowship with Richard Cookson at the University of Southampton was followed by a few years of pharmaceutical industrial experience. His fulltime academic career involved the Un...

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Format:HardcoverDimensions:1270 pages, 9.41 × 7.24 × 0.98 inPublished:April 7, 2014Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:012417034X

ISBN - 13:9780124170346

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Table of Contents

Chapter 1 - Introduction Section A - SUBSTITUTION RELATED PROCESSES Chapter 2 - Alkylation and Related Reactions I Chapter 3 - Alkylation and Related Reactions II Chapter 4 - Alkylation and Related Reactions III Chapter 5 - Alkylation and Related Reactions IV Section B - ADDITION TO UNSATURATED SYSTEMS Chapter 6 - Electrophilic Related Addition To C=C Chapter 7 - Conjugate Addition I Chapter 8 - Conjugate Addition II Chapter 9 - Conjugate Addition III Chapter 10 - Addition To C=N Bonds Chapter 11 - Addition To C=O Bonds I Chapter 12 - Addition To C=O Bonds II Chapter 13 - Addition To C=O Bonds III Section C - PERICYCLIC AND RELATED REACTIONS Chapter 14 - Cycloadditions I Chapter 15 - Cycloadditions II Chapter 16 - Rearrangements Section D - MISCELLANEOUS PROCESSES Chapter 17a - Kinetic Resolution-Related React Chapter 17b - Miscellaneous Reactions