Late-Life Depression

Hardcover | July 15, 2004

EditorSteven P. Roose, Harold A. Sackeim

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We live in an aging world. Illnesses that are prevalent and cause significant morbidity and mortality in older people will consume an increasing share of health care resources. One such illness is depression. This illness has a particularly devastating impact in the elderly because it is oftenundiagnosed or inadequately treated. Depression not only has a profound impact on quality of life but it is associated with an increased risk of mortality from suicide and vascular disease. In fact for every medical illness studied, e.g. heart disease, diabetes, cancer, individuals who are depressedhave a worse prognosis. Research has illuminated the physiological and behavioral effects of depression that accounts for these poor outcomes. The deleterious relationship between depression and other illnesses has changed the concept of late-life depression from a "psychiatric disorder" that isdiagnosed and treated by a psychiatrist to a common and serious disorder that is the responsibility of all physicians who care for patients over the age of 60. This is the first volume devoted to the epidemiology, phenomenology, psychobiology, treatment and consequences of late-life depression. Although much has been written about depressive disorders, the focus has been primarily on the illness as experienced in younger adults. The effects of aging onthe brain, the physiological and behavioral consequences of recurrent depression, and the impact of other diseases common in the elderly, make late-life depression a distinct entity. There is a compelling need for a separate research program, specialized treatments, and a book dedicated to thisdisorder. This book will be invaluable to psychiatrists, gerontologists, clinical psychologists, social workers, students, trainees, and others who care for individuals over the age of sixty.

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We live in an aging world. Illnesses that are prevalent and cause significant morbidity and mortality in older people will consume an increasing share of health care resources. One such illness is depression. This illness has a particularly devastating impact in the elderly because it is oftenundiagnosed or inadequately treated. Depres...

Steven P. Roose is at New York State Psychiatric Institute. Harold A. Sackeim is at New York University.

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Format:HardcoverDimensions:420 pages, 8.58 × 11.1 × 1.1 inPublished:July 15, 2004Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0195152743

ISBN - 13:9780195152746

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Table of Contents

IntroductionPART I EPIDEMIOLOGY AND THE BURDEN OF ILLNESS1. Dan G. Blazer: The Epidemiology of Depressive Disorders in Late Life2. Barry D. Lebowitz and Jason T. Olin: The Social and Financial Burden of Late-Life Depression to Society and IndividualsPART II THE PHENOMENOLOGY AND DIFFERENTIAL DIAGNOSIS OF LATE-LIFE MOOD DISORDERS3. George S. Alexopoulos and William Apfeldorf: Unipolar Depression4. Robert C. Young: Bipolar Disorders5. D.P. Devanand: Dysthymic Disorder in the Elderly6. Anand Kumar, Helen Lavretsky, and Virginia Elderkin-Thompson: Non-Major Clinically Significant Depression in the Elderly7. Helen Lavretsky and Gary W. Small: Mixed Cognitive and Depressive Syndromes8. Yeates Conwell: Suicide9. Paula J. Clayton: Bereavement and DepressionPART III THE PSYCHOBIOLOGY OF LATE-LIFE DEPRESSION10. Wilfred G. van Gorp, James C. Root, and Harold A. Sackeim: Neuropsychological Assessment of Late-Life Depression11. Structural and Functional Brain Imaging in Late-Life Depression Harold A. Sackeim12. K.R. Ranga Krishnan: Late-Life Depression and the Vascular Hypothesis13. Jennifer Keller, Theresa M. Buckley, and Alan F. Schatzberg: Hypothalmic-Pituitary-Adrenal Axis Activity in Mood and Cognition in the Elderly: Implications for Symptoms and Outcomes14. Stuart N. Seidman: The Neuroendocrinology of AgingPART IV TREATMENT15. Bruce G. Pollock: Pharmacokinetics and Pharmacodynamics in Late Life16. Steven P. Roose and Harold A. Sackeim: Antidepressant Medication for the Treatment of Late Life Depression17. Carl Salzman: Antidepressant Side Effects18. Charles L. Bowden and Nancy U. Karren: Mood Stabilizers19. J. Craig Nelson and Leon J. Epstein: Stimulants20. Christian R. Dolder, Jonathan P. Lacro, and Dilip V. Jeste: Antipsychotics21. Harold A. Sackeim: Electroconvulsive Therapy in Late-Life Depression22. John L. Beyer and P. Murali Doraiswamy: Pharmacologic Treatment of Depression in Alzheimer's Disease23. Charles F. Reynolds III, Patricia A. Arean, Thomas R. Lynch, and Ellen Frank: Psychotherapy in Old-Age Depression: Progress and Challenges24. Ira R. Katz and Joel Streim: Treatment of Depression in Residential SettingsPART V. DEPRESSION CO-MORBID WITH OTHER ILLNESSES25. Steven P. Roose and Alexander H. Glassman: Depression co-Morbid with Ischemic Heart Disease26. Robert G. Robinson: Vascular Disease and Late-Life Depression: Stroke27. David W. Oslin: Substance Abuse and Co-Morbidity28. Anjan Chatterjee and Karen Marder: Basal Ganglia Disease and Depression29. George S. Zubenko: Major Depressive Disorder in Alzheimer's Disease

Editorial Reviews

"This is an important book...it will become the standard reference book for all major topics under the rubric of late-life depression."--International Journal of Geriatric Psychiatry