Left Ventricular Hypertrophy: Physiology versus Pathology by Ernst E. Van der WallLeft Ventricular Hypertrophy: Physiology versus Pathology by Ernst E. Van der Wall

Left Ventricular Hypertrophy: Physiology versus Pathology

EditorErnst E. Van der Wall, A. van der Laarse, Babette M. Pluim

Paperback | October 11, 2012

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The importance of left ventricular hypertrophy (LVH) in cardiovascular disease has gained wide recognition. LVH is a highly important risk factor associated with major cardiovascular events, including symptomatic heart failure, particularly in patients with systemic hypertension. In recent years much has been learned about the genetics, molecular background, prevalence, incidence and prognosis of LVH. A variety of noninvasive methods has emerged for detecting LVH and the assessment of reversal of hypertrophy, yet a lot of controversy remains about the connotations and clinical implications of LVH. For instance, in the athlete's heart LVH may constitute a physiological adaptation to pressure overload, which normalizes following discontinuation of strenuous physical activity. On the other hand, in particular in patients with hypertension, LVH denotes a serious prognosis in the course of hypertension. In these patients LVH should be regarded as a grave prognostic sign rather than an innocent compensatory phenomenon. The distinction between physiologic and pathophysiologic LVH is the basis for this book. Left Ventricular Hypertrophy - Physiology versus Pathology is a bibliographical reflection of a Boerhaave Symposium held on April 9, 1999, in Leiden, The Netherlands. At this symposium the major issues in dealing with LVH were discussed, including etiology, genetics, detection, and therapy. In particular, the book includes novel detection methods for LVH such as magnetic resonance imaging and spectroscopy. Furthermore, much attention was paid to the molecular and genetic approach of LVH. This book will assist clinical cardiologists, fellows in cardiology, general internists, radiologists, cardiothoracic surgeons, biochemists, physiologists, pharmacologists, and basic research fellows in understanding the most recent insights in the background of physiologic versus pathologic LVH.
Title:Left Ventricular Hypertrophy: Physiology versus PathologyFormat:PaperbackDimensions:192 pages, 9.45 × 6.3 × 0.03 inPublished:October 11, 2012Publisher:Springer NetherlandsLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:9401058555

ISBN - 13:9789401058551


Table of Contents

Foreword. List of Contributors. 1. Etiology of left ventricular hypertrophy; A. van der Laarse, et al. 2. The role of vascular failure in heart failure; R.A. Tio, et al. 3. Perfusion abnormalities in the hypertrophied left ventricle: Link between compensated hypertrophy and heart failure? D.J.G.M. Duncker. 4. Assessment of left ventricular hypertrophy: a comparison of electrocardiography, echocardiography and magnetic resonance imaging; A.J. Brees, et al. 5. Hypertrophy and hypertension; J.J. Schipperheijn. 6. Left ventricular hypertrophy: pathology versus physiology; B.M. Pluim, et al. 7. The athlete's heart: a physiological or a pathological phenomenon? B.M. Pluim, et al. 8. Left ventricular hypertrophic heart disease studied by MR imaging and 31P-MR spectroscopy; H.J. Lamb, et al. 9. Hypertrophy and arrhythmias; A.A.M. Wilde. 10. Left ventricular hypertrophy: reversal by antihypertensive therapy; A. van der Laarse, E.E. van der Wall. 11. Postoperative regression of left ventricular hypertrophy; L.H.B. Baur, et al. 12. Myocardial hypertrophy and failure: a molecular approach; J.M. van Dantzig, et al. 13. Hypertrophy: clinical relevance of genotype. Einthoven lecture 1999; K. Schwartz. Index.

Editorial Reviews

`This book presents an excellent overview of today's understanding of left ventricular hypertrophy and the research directions that are being pursued. It is therefore of great value for all medical specialists and basic scientists who are interested in this field.' Johan H.C. Reiber in International Journal of Cardiac Imaging, 16 (2000)