Lentiviral Vectors by Didier TronoLentiviral Vectors by Didier Trono

Lentiviral Vectors

byDidier TronoEditorDidier Trono

Hardcover | December 14, 2001

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For the first time a compilation of chapters that depict the biological bases underlying the development of lentiviral vectors, the techniques involved in the manufacture of this new gene delivery tool, and its most promising applications.
Title:Lentiviral VectorsFormat:HardcoverDimensions:269 pagesPublished:December 14, 2001Publisher:Springer Berlin HeidelbergLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3540421904

ISBN - 13:9783540421900


Table of Contents

Introduction.-Molecular biology of lentivirus-mediated gene transfer.-HIV-derived lentiviral vectors.-SIV-derived lentiviral vectors.-Non-primate lentiviral vectors.-Production of lentiviral vectors.-Biosafety issues in lentiviral vector production.-Lentiviral vector targeting.-Integration site selection by lentiviruses: biology and possible control.-Improving the posttranscriptional aspects of lentiviral vectors.- Lentiviruses as vectors for CNS diseases.-Lentiviral vectors for the gene therapy of lympho-hematological disorders.-Lentiviral vectors for gene therapy of HIV-induced disease.-Opportunities for the use of lentiviral vectors in human gene therapy.-Subject index