Lentiviral Vectors by Didier TronoLentiviral Vectors by Didier Trono

Lentiviral Vectors

byDidier Trono

Paperback | November 17, 2012

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For the first time a compilation of chapters that depict the biological bases underlying the development of lentiviral vectors, the techniques involved in the manufacture of this new gene delivery tool, and its most promising applications.
Title:Lentiviral VectorsFormat:PaperbackDimensions:260 pagesPublished:November 17, 2012Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:364262667X

ISBN - 13:9783642626678

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Table of Contents

Introduction.-Molecular biology of lentivirus-mediated gene transfer.-HIV-derived lentiviral vectors.-SIV-derived lentiviral vectors.-Non-primate lentiviral vectors.-Production of lentiviral vectors.-Biosafety issues in lentiviral vector production.-Lentiviral vector targeting.-Integration site selection by lentiviruses: biology and possible control.-Improving the posttranscriptional aspects of lentiviral vectors.- Lentiviruses as vectors for CNS diseases.-Lentiviral vectors for the gene therapy of lympho-hematological disorders.-Lentiviral vectors for gene therapy of HIV-induced disease.-Opportunities for the use of lentiviral vectors in human gene therapy.-Subject index