Life Unfolding: How the human body creates itself by Jamie A. Davies

Life Unfolding: How the human body creates itself

byJamie A. Davies

Paperback | October 28, 2015

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Where did I come from? Why do I have two arms but just one head? How is my left leg the same size as my right one? Why are the fingerprints of identical twins not identical? How did my brain learn to learn? Why must I die? Questions like these remain biology's deepest and most ancient challenges. They force us to confront a fundamental biological problem: how can something as large and complex as a human body organize itself from the simplicity of a fertilized egg? A convergence of ideas from embryology, genetics,physics, networks, and control theory has begun to provide real answers. Based on the central principle of 'adaptive self-organization', it explains how the interactions of many cells, and of the tiny molecular machines that run them, can organize tissue structures vastly larger than themselves,correcting errors as they go along and creating new layers of complexity where there were none before. Life Unfolding tells the story of human development from egg to adult, from this perspective, showing how our whole understanding of how we come to be has been transformed in recent years. Highlighting how embryological knowledge is being used to understand why bodies age and fail, Jamie A. Daviesexplores the profound and fascinating impacts of our newfound knowledge.

About The Author

Since 1995, Jamie A. Davies has run his own laboratory at the University of Edinburgh, with a multi-disciplinary focus on discovering how mammalian organs construct themselves and how we can use this knowledge to build new tissues and organs for those in need. He has published around 90 research papers in the field of mammalian develop...
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Details & Specs

Title:Life Unfolding: How the human body creates itselfFormat:PaperbackDimensions:320 pages, 7.72 × 5.08 × 0.03 inPublished:October 28, 2015Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199673543

ISBN - 13:9780199673544

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Extra Content

Table of Contents

AcknowledgementsEthical StatementIntroduction1. Confronting an alien technology2. From one cell to many3. Making a difference4. Laying down a body plan5. Beginning a brain6. Long division7. Fateful conversations8. Great migrations9. Plumbing10. Organizing organs11. Taking up arms12. The Y and how13. Wired14. Dying to be human15. Making your mind up16. A sense of proportion17. Making friends and facing enemies18. Maintenance mode19. PerspectivesGlossaryFurther readingReferences

Editorial Reviews

`Review from previous edition A demanding but wonder-filled account of the simple interactions that create complex structures 'New Scientist