Long-Range Control of Gene Expression

Hardcover | March 3, 2008

byVeronica Van HeyningenEditorRobert E Hill

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This volume covers the current progress in understanding the mechanisms for genomic control of gene expression, which has grown considerably in the last few years as insight into genome organization and chromatin regulation has advanced. * Discusses the evolution of cis-regulatory sequences in drosophila* Includes information on genomic imprinting and imprinting defects in humans*Includes a chapter on epigenetic gene regulation in cancer

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This volume covers the current progress in understanding the mechanisms for genomic control of gene expression, which has grown considerably in the last few years as insight into genome organization and chromatin regulation has advanced. * Discusses the evolution of cis-regulatory sequences in drosophila* Includes information on genomi...

Format:HardcoverDimensions:416 pages, 9 × 6 × 0.98 inPublished:March 3, 2008Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0123738814

ISBN - 13:9780123738813

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Table of Contents

Chromatin Structure and the Regulation of Gene Expression: The Lessons of Pev in Drosophila

Polycomb Group Proteins and Long-Range Gene Regulation

Evolution of cis-Regulatory Sequences in Drosophila

Beta Globin Regulation and Long-Range Interactions

Long-Range Regulation of Ñ-globin Gene Expression

Global Control Regions and Regulatory Landscapes in Vertebrate Development and Evolution

Regulation of Imprinting in Clusters: Noncoding RNAs Versus Insulators

Genomic Imprinting and Imprinting Defects in Humans

Epigenetic Gene Regulation in Cancer

Genomic Identification of Regulatory Elements by Evolutionary Sequence Comparison and Functional Analysis

Regulatory Variation and Evolution and Implications for Disease

Organization of Conserved Elements Near Key Developmental Regulators in Vertebrate Genomes

Long-Range Gene Control and Genetic Disease
Dirk A. Kleinjan and Laura A. Lettice