Macrophages and Related Cells by Michael A. HortonMacrophages and Related Cells by Michael A. Horton

Macrophages and Related Cells

byMichael A. Horton

Paperback | April 25, 2013

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To produce a comprehensive overview of macrophages and related cell types in a short review volume is an impossible task. When I selected the topics to be included, some equally important areas were omitted by necessity, and for this I apologize. My choices have been somewhat eclectic, touching subjects of personal interest (such as osteoclast biology and macrophage electrophysiology) or of current fashion (apopto­ sis, antigen processing, cell adhesion molecules). The book has also had to encompass areas of a more general flavor to provide balance for the general reader (such as reviews of macrophage development, heterogeneity, and function, and of the surface molecules expressed by macrophages). I thank all the authors for their prompt sub­ missions; all have been of high quality, and my editorial tasks, thankfully, have been minimal. Michael A. Horton London, United Kingdom ix Contents Chapter J An Overview of Receptors of MPS Cells lain Fraser and Siam on Gordon 1. Introduction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 2. The Mononuclear Phagocyte System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 3. Diversity of Macrophage Plasma Membrane Receptors. . . . . . . . . . . . . . . . 6 3. 1 A Structural Approach to Classification . . . . . . . . . . . . . . . . . . . . . . . . . . 6 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 3. 2 Multisubunit Receptors 3. 3 Soluble Receptors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 3. 4 Lectins and Lectin-Like Receptors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 4. Functions and Selected Examples. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 4. 1 Growth, Differentiation, and Modulation . . . . . . . . . . . . . . . . . . . . . . . . 14 4. 2 Cell-Cell and Cell-Matrix Interactions. . . . . . . . . . . . . . . . . . . . . . . . . . . 16 4. 3 Endocytosis and Scavenger Receptors. . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 4. 4 Secretory Responses and Biosynthesis of Effector Molecules . . . . . . 17 5. Concluding Remarks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 6. References. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 . . . . . . . . . . . . . . . . . . . .
Title:Macrophages and Related CellsFormat:PaperbackDimensions:434 pagesPublished:April 25, 2013Publisher:Springer NatureLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:147579536X

ISBN - 13:9781475795363

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Table of Contents

An Overview of Receptors of MPS Cells; I. Fraser, S. Gordon. Heterogeneity of Mononuclear Phagocytes; P.J.M. Leenan, P.A. Campbell. Origin of Macrophages; L.A. Ginsel. Complement and the Mononuclear Phagocyte System; D. Lappin, K. Whaley. Macrophages and Prostaglandins; J.A. Hamilton. Antigen Processing; B.M. Chain, T.P. Levine. Antigens of Osteoclasts; M.H. Helfrich, M.A. Horton. Electrophysiology of Osteoclasts and Macrophages; S.J. Dixon, et al. Complement Receptors; S.K.A. Law. Fcy Receptors of Myeloid Cells; M. de Haas, et al. Matrix Receptors of Myeloid Cells; E.J. Brown, F.P. Lindberg. Leukocyte Integrins; I. Dransfield. Molecular Basis for Leukocyte Adhesion Molecule Deficiency; M.A. Arnaout. Carbohydrate-Recognition Proteins of Macrophages and Related Cells; M.E. Taylor. Leukocyte Adhesion to Endothelium; M.H. Thornhill, D.O. Haskard. Cell Recognition of Apoptotic Cells; C.A. Smith, et al. Index.