Malignant Pleural Mesothelioma

Hardcover | December 14, 2006

EditorKenneth OByrne, Valerie Rusch

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Malignant pleural mesothelioma, a malignancy due largely to asbestos exposure, represents an increasingly common challenge to clinical and medical oncologists, respiratory physicians, and cardiothoracic surgeons, as well as researchers in the field. The disease has yet to reach its peak and isexpected to kill over 100,000 people worldwide. As malignant pleural mesothelioma gains in profile, Kenneth O'Byrne and Valerie Rusch present a comprehensive overview of the subject, aimed at all health care professionals who come into contact with patients with the disease. The book includes chapters on epidemiology, diagnosis, histopathology, radiology, surgery, chemotherapy, immune therapy, radiotherapy, and palliative medicine, written by an international team of contributors. A molecular biology section focuses on the carcinogenic effects of asbestos fibres andsimian virus 40, angiogenesis and angiogenic growth factors, the immune response, and genetic abnormalities detected in the disease. Future therapies are also covered, as is a perspective on the distinct legal issues related to the disease. This highly-illustrated, full colour book provides theultimate, timely resource on this devastating disease.

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From the Publisher

Malignant pleural mesothelioma, a malignancy due largely to asbestos exposure, represents an increasingly common challenge to clinical and medical oncologists, respiratory physicians, and cardiothoracic surgeons, as well as researchers in the field. The disease has yet to reach its peak and isexpected to kill over 100,000 people worldw...

Dr Ken O'Byrne is President of the British Mesothelioma Trust. Professor Valerie Rusch, M.D. is currently Chief of Thoracic Surgery at Memorial Sloan-Kettering Cancer Center, where she also holds the William G. Cahan Chair. She is a member of the Editorial Boards for The Journal of Thoracic and Cardiovascular Surgery, The Journal of...
Format:HardcoverDimensions:480 pages, 9.69 × 6.73 × 1.12 inPublished:December 14, 2006Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0198529309

ISBN - 13:9780198529309

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Table of Contents

Section 1. Clinical Features of Mesothelioma1. Juliet E King and Philip S Hasleton: The Epidemiology and Aetiology of Malignant Mesothelioma2. AW Musk, NH de Klerk, Jacek Niklinski, Wieslawa Niklinska, Elzbieta Chyczewska, Jerzy Laudanski, Wojciech Naumnik, Lech Chyczewski, Eric Pluygers, Raymond P Abratt, Daniel A Vorobiof, Neil White, Salih Emri, Murat Tuncer and Izzettin Baris: Epidemiological Snapshots From Around the World3. Michael D Peake and James Entwisle and Steven Gray: Clinical Presentation, Radiological Evaluation and Diagnosis4. Juliet King, Francoise Galateau-Salle and Philip Hasleton: Histopathology of Malignant Pleural Mesothelioma5. J.A Burgers and J.P.J.J Hegmans: Clinico-Pathological Prognostic Factors and Scoring Systems in Malignant Pleural MesotheliomaSection 2. Biology of Mesothelioma6. BT Mossman and William Swain: Carcinogenic Mechanisms in Mesothelioma: Effects of asbestos on cell signal events, transcription factors, and inflammatory cytokines7. Amy Powers, Maurizio Bocchetta and Michele Carbone: Viral Factors in the Pathogenesis of Malignant Mesothelioma8. John G Edwards, Uwe Zangemeister-Wittke and Kenneth J O'Byrne: Growth Factors, Cyclooxygenease-2 and Matrix Metalloproteinases in Malignant Mesothelioma9. Peter B Vermeulen, Roberto Salgado and Eric A Van Marck: Vascularisation in Malignant Mesothelioma10. AM Smith, S Lansley, C Jackaman, B Koloska, S Broomfield, Bruce W.S Robinson and D.J Nelson: Immunobiology of Malignant Mesothelioma11. Deborah A Altomare and Joseph R Testa: Cytogenetic and Molecular Genetic Changes in Malignant MesotheliomaSection 3. Treatment Strategies12. David A Waller and Antonio E Martin-Ucar: The Role of Surgery for Diagnosis, Staging and Symptom Control in Malignant Pleural Mesothelioma13. Daniel J Boffa and Valerie W Rusch: Surgical and Multimodality Approaches to the Management of Operable Malignant Mesothelioma14. Jeremy P.C Steele and Robin M Rudd: Systemic Chemotherapy for Malignant Pleural Mesothelioma15. Craig W Stevens, Kenneth M Forster and W. Roy Smythe: Radiotherapy for Mesothelioma16. Mary ER O'Brien, Ander Urruticoechea Ribate and Bernard Souberbielle: Immunotherapy for Malignant Mesothelioma17. Paul Baas: Intra-thoracic Photodynamic Diagnosis and Treatment with Photodynamic Therapy or Hyperthermia of Malignant Mesothelioma18. Fiona Blackhall, Sofia Baka, Sarah Danson and Malcolm Ranson: Novel Therapies for Mesothelioma19. Daniel H Sterman and Peter A DeLong: Gene Therapy for Malignant Pleural Mesothelioma20. Sam Ahmedzai and Helen Clayson: Palliative Care for Mesothelioma21. Adrian Budgeon and John Ned Lipsitz: The Treatment of Mesothelioma Cases in the American and United Kingdom Legal Systems

Editorial Reviews

"Anybody dealing with diffuse malignant mesothelioma, in either a research or clincial setting, should learn a great deal from this book in topics outside his or her own immediate specializations. As this clinically relentless disease continues to increase but has proven so refractory to therapy, any additional knowledge is welcome ideed, and this book is also welcome indeed."--Respiratory Care "A comprehensive overview of the subject, aimed at all health care professionals who come into contact with patients with the disease."--Anticancer Research