This book represents the final work of the late Professor C. David Marsden, who was without doubt the most influential figure in the field of movement disorders, in terms of his contributions to both research and clinical practice, in the modern era. Originally prepared and written inconjunction with his colleague at the Institute of Neurology, Prof. Ivan Donaldson, David Marsden had intended for this book to be the most comprehensive reference book on movement disorders, but also that it would serve as the "clinical Bible" for the management of these conditions. The book covers the full breadth of movement disorders, from the underlying anatomy and understanding of basal ganglia function to the diagnosis and management of specific movement disorders, including the more common conditions such as Parkinson's Disease through to the rare and very rareconditions such as Neimann-Pick disease. Chapters follow a structured format with historical overviews, definitions, clinical features, differential diagnosis, investigations and treatment covered in a structured way. The book is extensively illustrated, with many original photographs and diagramsof historical significance that have not published before. Among these illustrations are still images of some original film clips of some of Dr. Marsden's patients published here for the first time. Comprehensively referenced and updated by experts from the Institute of Neurology at Queen Square,this book will provide a valuable reference for not just movement disorder specialists and researchers, but also for clinicians who care for patients with movement disorders.