Mass Spectrometry For The Novice: A Basic Approach by John GreavesMass Spectrometry For The Novice: A Basic Approach by John Greaves

Mass Spectrometry For The Novice: A Basic Approach

byJohn Greaves, John RobozEditorJohn Greaves

Paperback | October 16, 2013

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With usage of mass spectrometry continually expanding, an increasing number of scientists, technicians, students, and physicians are coming into contact with this valuable technique. Mass spectrometry has many uses, both qualitative and quantitative, from analyzing simple gases to environmental contaminants, pharmaceuticals, and complex biopolymers. The extraordinary versatility can make mass spectrometers daunting to novices. Consequently, new users would benefit greatly from an understanding of the basic concepts as well as the processes that occur in these instruments.Mass Spectrometry for the Noviceprovides exactly that, with detailed, straightforward descriptions and clear illustrations of principles of operations and techniques.

The book begins with an overview that includes essential definitions and then provides information on the components of and the strategies used in the most common instruments. The authors discuss the methodologies available, classes of compounds analyzed, and the types of data that can be generated. A group of representative applications from published articles is summarized, demonstrating the diversity of mass spectrometry. The authors also condense the essentials of the topic into one invaluable chapter that provides a set of concise take-home messages on all aspects of mass spectrometry. The final section provides a collection of resources including books, reviews, and useful websites.

Using simple language, new color figures, clever cartoons, and assuming no prior knowledge, this book provides a readily understandable entr'to mass spectrometry. A CD-ROM with selected figures and cartoons is included.

John Greavesis director of the Mass Spectrometry Facility in the Department of Chemistry, University of California, Irvine. He received his BSc in zoology and genetics from Leeds University in 1975 and a PhD, on the pharmacology of the antimalarial Primaqiune, from Liverpool University/Liverpool School of Tropical Medicine in 1979. On ...
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Title:Mass Spectrometry For The Novice: A Basic ApproachFormat:PaperbackDimensions:309 pages, 9 × 6.1 × 0.7 inPublished:October 16, 2013Publisher:Taylor and FrancisLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1420094181

ISBN - 13:9781420094183

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Table of Contents

An Overview
A Brief History
Definitions Concerning Instruments, Mass,m/z, and Ions
Components of Instrument and Their Functions
Definitions Concerning Instrument Performance
Definitions Concerning Applications
Information from Mass Spectra
Diversity and Scope of Applications

Instrumentation
Sample Introduction
Ion Sources and Methods of Ionization
Mass Analyzers
Ion Current Detectors
Vacuum Systems
Data Systems

Methodologies and Strategies
Measures of Instrument Performance
Interpretation of Mass Spectra
Analytical Techniques and Strategies
Omics
Biopolymers
Imaging Mass Spectrometry
Bioinformatics
Buying a Mass Spectrometer

Examples from Representative Publications
An Open-Access Mass Spectrometry Facility
Environmental: Organochlorines in Fish
Environmental: Pharmaceuticals in Surface and Wastewaters
Pharmacology: Lipitor Metabolism
New Techniques: Paper Spray of Pharmaceuticals
Petroleomics: Crude Oil Characterization
Metabolomics: Disease Markers for a Tropical Disease
Metabolomics: Chemical Defense
Lipidomics: Coronary Artery Disease
Proteomics: Protein Identification in a Painting
Proteomics: Protein Identification and Metastasis
Proteomics: Noncovalent Interactions
Tissue Imaging

The Absolute Essentials
General
Instrument Components
Performance Parameters
Techniques and Strategies

Resources
Books, Journals, Review Articles, Classical Publications
Major Instrument Manufacturers
Mass Spectrometry Societies, Blogs, and Discussion Groups
The Mass Spectrometrist and the Internet