Maximal Myocardial Perfusion as a Measure of the Functional Significance of Coronary Artery Disease: From a Pathoanatomic to a Pathophysiologic Interp by N.H. Pijls

Maximal Myocardial Perfusion as a Measure of the Functional Significance of Coronary Artery Disease…

byN.H. Pijls

Kobo ebook | December 6, 2012

Pricing and Purchase Info

$86.09 online 
$107.53 list price save 19%

Prices and offers may vary in store

Available for download

Not available in stores

about

Coronary flow reserve is a functional measure of stenosis severity re­ flecting the integrated effects of its geometry including percent stenosis, absolute lumen area, length and shape. Its clinical application has been primarily qualitative in non-invasive, perfusion imaging. Measurement of coronary flow reserve during routine coronary arte­ riography has been an elusive goal. Transit time and indicator dilution techniques for assessing coronary flow reserve at cardiac catheteriza­ tion are associated with marked variability compared to microspheres or flow meters, thereby making their use questionable in comparison to the precision of good quantitative arteriography. Coronary flow reserve measured by special Doppler catheters as an adjunct to coronary arte­ riography shows in man the value of this integrated functional measure of stenosis severity and the limitations of percent diameter narrowing as a measure of its physiologic significance. However, Doppler catheters require additional instrumentation that is not yet an integral part of coronary arteriography and provide measures of absolute coronary flow reserve only. Relative maximum flow or relative flow reserve has been demon­ strated to be an important independent, complimentary descriptor of stenosis severity independent of fluctuating hemodynamic conditions. The method developed for DSA by Nico Pijls, described in this book is the first approach for assessing relative coronary flow reserve as a part of routine coronary arteriography by DSA. The theory and basic con­ cepts are well developed, experimental validation thorough and clinical applications timely.

Title:Maximal Myocardial Perfusion as a Measure of the Functional Significance of Coronary Artery Disease…Format:Kobo ebookPublished:December 6, 2012Publisher:Springer NetherlandsLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:9401134987

ISBN - 13:9789401134989

Look for similar items by category:

Reviews