Mechanisms of Mitotic Chromosome Segregation by J. Richard McIntoshMechanisms of Mitotic Chromosome Segregation by J. Richard McIntosh

Mechanisms of Mitotic Chromosome Segregation

Guest editorJ. Richard McIntosh

Paperback | May 4, 2017

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This book describes current knowledge about the mechanisms by which cells segregate their already duplicated chromosomes in preparation for cell division. Experts in the field treat several important aspects of this subject: (1) the history of research on mitotic mechanisms, to serve as a background; (2) assembly of the mitotic spindle; (3) Kinetochore assembly and function; (4) the mechanisms of chromosome congression to the metaphase plate; (5) the spindle assembly checkpoint; (6) mechanisms to avoid and correct erroneous chromosome attachments to the spindle; (7) a molecular perspective on spindle assembly in land plants; (8) chromosome segregation in anaphase A; (9) spindle elongation in anaphase B; and (10) the consequences of errors in chromosome segregation. Each chapter provides the reader with a comprehensive and accurate picture of current research in a form that is both readable and authoritative. The volume is suitable for scholars in this and related fields and for teaching at an advanced level.

Title:Mechanisms of Mitotic Chromosome SegregationFormat:PaperbackProduct dimensions:340 pages, 9.61 × 6.69 × 0.92 inShipping dimensions:9.61 × 6.69 × 0.92 inPublished:May 4, 2017Publisher:MDPI AGLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3038424021

ISBN - 13:9783038424024


Table of Contents

1) A Brief History of Research on Mitotic Mechanisms
2) Metaphase Spindle Assembly
3) A Molecular View of Kinetochore Assembly and Function
4) Mechanisms of Chromosome Congression during Mitosis
5) A Cell Biological Perspective on Past, Present and Future Investigations of the Spindle Assembly Checkpoint
6) Mechanisms to Avoid and Correct Erroneous Kinetochore-Microtubule Attachments
7) Mitotic Spindle Assembly in Land Plants: Molecules and Mechanisms
8) Anaphase A: Disassembling Microtubules Move Chromosomes toward Spindle Poles
9) Anaphase B
10) The Consequences of Chromosome Segregation Errors in Mitosis and Meiosis