Mechanisms of Morphogenesis

Other | October 1, 2005

byDavies, Jamie, Jamie Davies

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Morphogenesis is the set of processes that generate shape and form in the embryo- an important area within developmental biology. An exciting and up to the minute account of the very latest research into the factors that create biological form,Mechanisms of Morphogenesisis a text reference on the mechanisms of cell and tissue morphogenesis in a diverse array of organisms including prokaryotes, animals, plants and fungi.

By combining hard data with computer modelling, this book will equip readers with a much broader understanding of the scope of modern research than is otherwise available. The book focuses on the ways in which the genetic programme is translated to generate cell shape, to direct cell migration, and to produce the shape, form and rates of growth of the various tissues. Each topic is illustrated with experimental data from real systems, with particular reference to gaps in current knowledge and pointers to future research.

* Includes over 200 four-color figures
* Offers an integrated view of theoretical developmental biology and computer modelling with laboratory-based discoveries
* Covers experimental techniques as a guide to the reader
* Organized around principles and mechanisms, using them to integrate discoveries from a range of organisms and systems

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Morphogenesis is the set of processes that generate shape and form in the embryo- an important area within developmental biology. An exciting and up to the minute account of the very latest research into the factors that create biological form,Mechanisms of Morphogenesisis a text reference on the mechanisms of cell and tissue morphogen...

Since 1995 Davies has run his own laboratory at the University of Edinburgh, with a multidisciplinary focus on discovering how mammalian organs construct themselves and howwe can use apply knowledge to build new tissues and organs for those in need. Some ofthe work of his 20-strong research team is 'conventional' developmental biology;...

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Format:OtherDimensions:384 pages, 1 × 1 × 1 inPublished:October 1, 2005Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0080454437

ISBN - 13:9780080454436

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Table of Contents

1) Introductory Section
1.1 General introduction
1.2 Key principles of morphogenesis
1.3 The power and limitations of self-assembly

2) Cell shape and the cell morphogenesis
2.1 Morphogenesis by changing cell shape: a brief overview
2.2 Shape in animal cells: tensegrity
2.3 Making cellular processes
2.4 Shape in plant cells

3) Cell Migration
3.1 Cell migration in development: a brief overview
3.2 The nanomachinery of locomotion
3.3 Guidance by chemotaxis
3.4 Guidance by galvanotaxis
3.5 Guidance by contact
3.6 Waypoint navigation in the embryo
3.7 Condensation of cells

4) Epithelial Morphogenesis
4.1 The epithelial state - brief overview
4.2 Neighbour exchange and convergent extension
4.3 Closure of holes
4.4 Invagination and evagination
4.5 Epithelial fusion
4.6 Epithelial Branching

5) Morphogenesis by cell proliferation and death
5.1 Growth, proliferation and death - a brief introduction
5.2 Morphogenesis by orientated cell division
5.3 Morphogenesis by elective cell death

6) Conclusion and perspectives