Mechanochemical Organic Synthesis

Hardcover | May 13, 2016

byDavor Margetic, Vjekoslav ` Trukil

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Mechanochemical Organic Synthesis is a comprehensive reference that not only synthesizes the current literature but also offers practical protocols that industrial and academic scientists can immediately put to use in their daily work. Increasing interest in green chemistry has led to the development of numerous environmentally-friendly methodologies for the synthesis of organic molecules of interest. Amongst the green methodologies drawing attention, mechanochemistry is emerging as a promising method to circumvent the use of toxic solvents and reagents as well as to increase energy efficiency. The development of synthetic strategies that require less, or the minimal, amount of energy to carry out a specific reaction with optimum productivity is of vital importance for large-scale industrial production. Experimental procedures at room temperature are the mildest reaction conditions essentially required for many temperature-sensitive organic substrates as a key step in multi-step sequence reactions and are the core of mechanochemical organic synthesis. This green synthetic method is now emerging in a very progressive manner and until now, there is no book that reviews the recent developments in this area. Features cutting-edge research in the field of mechanochemical organic synthesis for more sustainable reactions Integrates advances in green chemistry research into industrial applications and process development Focuses on designing techniques in organic synthesis directed toward mild reaction conditions Includes global coverage of mechanochemical synthetic protocols for the generation of organic compounds

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From the Publisher

Mechanochemical Organic Synthesis is a comprehensive reference that not only synthesizes the current literature but also offers practical protocols that industrial and academic scientists can immediately put to use in their daily work. Increasing interest in green chemistry has led to the development of numerous environmentally-friendl...

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Mechanochemical Organic Synthesiscompiles the current literature and also offers practical protocols that industrial and academic scientists can immediately apply in their daily work. With the widespread and increasing interest in green chemistry, numerous environmentally friendly methodologies for the synthesis of organic molecules ha...

Dr. Davor Margeti is senior research scientist and acting head of the division of organic chemistry and biochemistry at Ru er Boa kovi research Institute in Zagreb, Croatia. He is the head of the laboratory for physical organic chemistry and Professor of physical organic chemistry at Rijeka University.He graduated with a degree in chem...
Format:HardcoverDimensions:386 pages, 9.41 × 7.24 × 0.98 inPublished:May 13, 2016Publisher:Elsevier Science & TechLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0128021845

ISBN - 13:9780128021842

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Table of Contents

Tentative contents:

Preface Contents 1 Introduction 1.1. Historical Overview 1.2. Description of Technique 1.2.1. Laboratory Equipment 1.2.2. Technical Parameters 1.2.3. Chemical Parameters 1.2.4. Scale-up 1.3. Liquid Assisted Grinding (LAG), ILAG 2 Cycloaddition Reactions 3 Bond Formation Reactions 3.1. C-C Bond Formation Reactions 3.1.1. Heck Coupling 3.1.2. Sonogashira Coupling 3.1.3. Suzuki Coupling 3.1.4. Michael Addition 3.1.5. Morita-Baylis-Hillman reaction 3.1.6. Pinacol Reaction 3.1.7. Wittig Reaction 3.1.8. Horner-Wadsworth-Emmons Reaction 3.1.9. Aldol condensation 3.2. C-N Bond Formation Reactions 3.3. C-O Bond Formation Reactions 3.4. O-P Bond Formation Reactions 4 Oxidation and Reduction Reactions 5 Applications in Fullerene Chemistry 6 Miscellaneous Reactions 7 Applications in Supramolecular Chemistry 8 Experiments for Undergraduate Curriculum Subject Index