Mechanosensitivity of the Nervous System by N. TavernarakisMechanosensitivity of the Nervous System by N. Tavernarakis

Mechanosensitivity of the Nervous System

Foreword byN. Tavernarakis, P. PerssonEditorAndre Kamkin

Paperback | November 19, 2010

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This book presented the latest findings in mechanosensitivity of the nervous system. Nervous system stands out from a number of tissues because besides reacting to the mechanical stress it is transmitting its own response to other organs and tissues, which are located down stream of its signaling pathway. For this reason any type of mechanical stimulation of nervous system, which is capable of triggering a physiological response, has high scientific and practical significance, since it allows its use beyond a particular experimental model anywhere where it is contributing to a particular pathological condition. This book is a unique collection of reviews outlining the current knowledge and the future developments in this rapidly growing field. Currently, investigations of the effects of mechanical stress on nervous system are focused on several issues. The majority of studies investigate the effects of mechanical stimulation on mechanosensitive channels, as its primary target and interactive agent, and aim on description of downstream intracellular signaling pathways together with addressing general issues of biomechanics of the nervous system. Knowledge of biomechanics, and mechanisms, which underlie it on organism, organ, tissue and cellular level, is necessary for understanding of the normal functioning of living organisms and allows to predict changes, which arise due to alterations of their environment, and possibly will allow to develop new methods of artificial intervention. The book brings up the problem closer to the experts in related medical and biological sciences as well as practicing doctors besides just presenting the latest achievements in the field.
Title:Mechanosensitivity of the Nervous SystemFormat:PaperbackDimensions:372 pages, 9.25 × 6.1 × 0.03 inPublished:November 19, 2010Publisher:Springer NetherlandsLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:9048179653

ISBN - 13:9789048179657

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Table of Contents

Foreword by Nektarios TavernarakisForeword by Pontus PerssonEditorialContributorsPart I Mechanosensitivity of Nervous Cells 1. Mechanosensitive Channels in Neuronal and Astroglial Cells in the Nervous SystemSergei Kirischuk2. Ion Channels with Mechanosensitivity in the Nervous SystemGehoon Chung and Seog Bae Oh3. Mechanosensitive Cation Currents and their Molecular Counterparts in Mammalian Sensory NeuronsJizhe Hao, Matthieu Raoux, Nathalie Azorin, Lise Rodat-Despoix, Aurélie Giamarchi, François Maingret, Marcel Crest, Bertrand Coste, and Patrick Delmas4. Neurons and Cell Swelling-Induced Peptide Hormone SecretionVladimir Strbák5. Neuronal Mechanosensitivity in the Gastrointestinal TractScott D. SmidPart II Mechanosensitivity of the Receptors6. Mechanosensitivity of the CochleaKeiji Tabuchi and Akira Hara7. Osmoreceptors in cochlear outer hair cellsNarinobu Harada8. Are Stretch-Activated Channels an Ocular Barometer? James C. H. Tan and Minas T. Coroneo9. Neuromodulation of mechanosensory input to the insect CNS. Beulah Leitch and Robert M. PitmanPart III Biomechanic of Nervous System10. Biomechanics of the CNSKristian Franze, Andreas Reichenbach, and Josef Käs11. The neural representation of Kinematics and Dynamics in multiple brain regions: The use of force field reaching paradigms in the Primate and RatJoseph T. Francis12. Mechanical properties of brain tissue: Characterisation and constitutive modelling Hans A.W. van Dommelen, Matej Hrapko, and Gerrit W.M. Peters 13. Role of falx on brain stress-strain responsesNarayan Yoganandan, Jianrong Li, Jiangyue Zhang, and Frank A. Pintar14. Exercise and Nervous SystemKazuhiro Imai, Hiroyuki NakajimaPart IV Mechanosensitivity of Neurovascular System15. Mechanosensitive Calcium Fluxes in the Neurovascular Unit: TRP Channel Regulation of the Blood-Brain BarrierRachel C. Brown and Roger G. O'NeilIndex