Membrane Proteins as Drug Targets

Hardcover | August 24, 2010

byCharles.a LunnEditorCharles.a Lunn

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Membrane proteins continue to be prime drug targets because they perform essential processes in the cell including controlling the flow of information and materials between cells and mediating activities like hormone action and nerve impulses. The study of membrane proteins could lead to new and improved pharmaceutical treatments for a wide range of illnesses such as heart disease, cystic fibrosis and depression. This volume reviews the latest developments in the field. * Discusses new discoveries, approaches, and ideas in the field of membrane proteins and reviews how they are being used to develop new drugs * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields

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Membrane proteins continue to be prime drug targets because they perform essential processes in the cell including controlling the flow of information and materials between cells and mediating activities like hormone action and nerve impulses. The study of membrane proteins could lead to new and improved pharmaceutical treatments for a...

Format:HardcoverDimensions:270 pages, 9 × 6 × 0.98 inPublished:August 24, 2010Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0123812887

ISBN - 13:9780123812889

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Table of Contents

  1. Inverse Agonism at Serotonin and Cannabinoid Receptors

Vincent J. Aloyo, Kelly A. Berg, William P. Clarke, Umberto Spampinato, and John A. Harvey

    2. G protein-coupled receptor heteromers as new targets for drug development

      Sergi Ferré, Gemma Navarro, Vicent Casadó, Antoni Cortés, Josefa Mallol, Enric I. Canela, Carme Lluís and Rafael Franco

    3. Receptor activity modifying proteins and their potential as drug targets

      Denise L. Wootten, John Simms, Debbie L. Hay, Arthur Christopoulos and Patrick M. Sexto

      4. Regulators of G Protein Signaling Proteins As Targets For Drug Discovery

      Benita Sjögren, Levi L. Blazer and Richard R. Neubig

    5. Escorts Take the Lead: Molecular Chaperones as Therapeutic Targets

      Dumaine Williams and Lakshmi A. Dev

      6. The T1r2/T1r3 Sweet Receptor and Trpm5 Ion Channel: Taste Targets With Therapeutic Potential

      Dennis Sprous and R. Kyle Palmer

      7. Membrane-associated enzymatic synthesis

      Edward A. Esposito and Robert Weis

      Editorial Reviews

      PRAISE FOR THE SERIES: "Full of interest not only for the molecular biologist--for whom the numerous references will be invaluable--but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."--British Medical Journal