Metal Transporters

Other | October 5, 2012

byJose M. Arguello, Jose M. Arguello, Svetlana Lutsenko

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This volume of Current Topics in Membranes focuses on metal transmembrane transporters and pumps, a recently discovered family of membrane proteins with many important roles in the physiology of living organisms. The book summarizes the most recent advances in the field of metal ion transport and provides a broad overview of the major classes of transporters involved in homeostasis of heavy metals. Various families of the transporters and metal specificities are discussed with the focus on the structural and mechanistic aspects of their function and regulation. The reader will access information obtained through a variety of approaches ranging from X-ray crystallography to cell biology and bioinformatics, which have been applied to transporters identified in diverse biological systems, such as pathogenic bacteria, plants, humans and others.



  • Field is cutting-edge and a lot of the information is new to research community
  • Wide breadth of topic coverage
  • Contributors of high renown and expertise

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From the Publisher

This volume of Current Topics in Membranes focuses on metal transmembrane transporters and pumps, a recently discovered family of membrane proteins with many important roles in the physiology of living organisms. The book summarizes the most recent advances in the field of metal ion transport and provides a broad overview of the major ...

Format:OtherDimensions:456 pages, 1 × 1 × 1 inPublished:October 5, 2012Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0123946107

ISBN - 13:9780123946102

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Table of Contents

1. Metal ion physiology: Mechanistic approach

Svetlana Lutsenko

2. Transferrin mediated iron uptake

Anne B. Mason

3. Structure-function of siderophore-iron transporters

Isabelle J. Schalk

4. Iron transport machinery of human cells: players and their interactions

Caroline A. Enns

5. Mechanism of copper uptake in mammalian cells

Vinzenz Unger and Jack H. Kaplan

6. Heavy metal transport P-type ATPases

Amy C. Rosenzweig and Jose Argüello

7. CUS periplasmic Cu+ efflux system

Ninian J. Blackburn and Megan McEvoy

8. Molecular architecture and function of ZnT transporters

Taiho Kambe

9. Structure-function of ZIP transporters

Robert E. Dempski

10. Nramp family of transporters

Mathieu F. Cellier

11. Plant YSL metal transporters

Elsbeth Walker and Sarah S. Conte

12. Pathways of arsenic uptake and detoxification

Barry P. Rosen

13. Mechanisms of heme transport and trafficking

Angela Wilks

14. Mechanisms of Mg2+ and Co2+ transport

Said Eshaghi