Methods in Observational Epidemiology

Hardcover | May 15, 1996

byJennifer L. Kelsey, Alice S. Whittemore, Alfred S. Evans

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Providing a comprehensive picture of the design, conduct, analysis, and interpretation of non-experimental studies of both infectious and non-infectious diseases, the Second Edition of this widely used text has been thoroughly updated to take into account the numerous developments inepidemiology over the past decade. Since the first edition was published in 1986, additional sources of data have become available through the increasing use of computerized records for health-related purposes. Also, a better understanding of the uses and limitations of certain epidemiologicconcepts has been gained. Modifications of traditional study designs, including nested case-control studies and case-cohort studies, are now more frequently employed. Biological markers of exposure, disease susceptibility, and disease itself are used in many studies and methods of statisticalanalysis have been further developed. All of these developments have been considered in writing the Second Edition. The authors cover the full scope of observational studies, describing in detail cohort studies, case-control studies, cross-sectional studies, and epidemic investigation. The use of statistical procedures is described in easy-to-understand terms. Sample size estimation, sampling, measurement, andmeasurement error are fully discussed. Each chapter in the second edition has been updated and several chapters have been expanded. Chapter 3, which summarizes sources of data on disease occurrence, includes several additional sources of data. Chapter 5, which describes modifications of traditionalstudy designs, now contains nested case-control and case-cohort studies. Chapter 15, on other types of measurement, has been expanded to include sections on measurement in epidemiologic studies of the elderly and on biological markers since these have become major areas of epidemiologic research inrecent years. Much of the material in Chapters 6, 7, and 9 on the analysis of data from epidemiologic studies is also new to this edition. Perhaps the greatest challenge for the authors in writing this Second Edition was to make some of the modern, frequently used methods of statistical analysis understandable to readers with a limited mathematical or statistical background. Although this book is intended for readers who have hadintroductory courses in epidemiology and biostatistics, even readers who do not fully comprehend the theory behind some of the techniques should understand the rationale for their use and be able to interpret results when they appear on a computer printout or in the literature. The Second Edition ofthis widely used text will serve as a practical resource for students and practitioners of epidemiology, public health and biostatistics.

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From the Publisher

Providing a comprehensive picture of the design, conduct, analysis, and interpretation of non-experimental studies of both infectious and non-infectious diseases, the Second Edition of this widely used text has been thoroughly updated to take into account the numerous developments inepidemiology over the past decade. Since the first ed...

From the Jacket

Providing a comprehensive picture of the design, conduct, analysis, and interpretation of non-experimental studies of both infectious and non-infectious diseases, the second edition of this widely used text has been thoroughly updated to take into account the numerous developments in epidemiology over the past decade. Since the first e...

J. L. Kelsey is at Columbia University School of Public Health.

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Format:HardcoverDimensions:448 pages, 6.38 × 9.45 × 1.3 inPublished:May 15, 1996Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0195083776

ISBN - 13:9780195083774

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Table of Contents

1. Introduction2. Biologic and Statistical Concepts3. Sources of Routinely Collected Data on Disease Occurrence4. Prospective Cohort Studies: Planning and Execution5. Retrospective Cohort, Nested Case-Control and Case-Cohort Studies: Planning and Execution6. Cohort Studies: Statistical Analysis I7. Cohort Studies: Statistical Analysis II8. Case-Control Studies: Planning and Execution9. Case-Control Studies: Further Design Consideration and Statistical Analysis10. Crossd-Sectional and Other Types of Studies11. Epidemic Investigation12. Methods of Sampling and Estimation of Sample Size13. Measurement Error14. Measurement I: Questionnaires15. Measurement II: Other Types of Measurement

Editorial Reviews

"The second edition is a solid contribution to the field of epidemiology."--Chronic Diseases in Canada