Methods in Pharmacology: Molecular and Cellular Biology of Pharmacological Targets by H. GlossmannMethods in Pharmacology: Molecular and Cellular Biology of Pharmacological Targets by H. Glossmann

Methods in Pharmacology: Molecular and Cellular Biology of Pharmacological Targets

EditorH. Glossmann, J. Striessnig

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The current volume provides detailed experimental protocols used to study plasma membrane ion channels as pharmacological targets. Coverage includes molecular and biochemical characterization of ion channels; fuctional analysis of ion channels after reconstitution, expression, or in cells; and specific methods and tools. This wealth of information will benefit academic and industrial researchers and graduate students in pharmacology, biochemistry, physiology, and biophysics.

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Title:Methods in Pharmacology: Molecular and Cellular Biology of Pharmacological TargetsFormat:HardcoverDimensions:287 pages, 10 × 7.01 × 0.03 inPublisher:Springer US

The following ISBNs are associated with this title:

ISBN - 10:0306444240

ISBN - 13:9780306444241

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Table of Contents

Molecular and Biochemical Characterisation of Ion Channels: Purification and Pharmacologic Analysis of the OmegaConotoxin Receptor from Rat Brain (M. McEnery). Molecular Characterization of the CharybdotoxinSensitive, High Conductance, Calcium Activated Potassium Channel (M. GarciaCalco et al.). Functional Analysis of Ion Channels: Xenopus Oocytes as an Expression System for Ion Channels (A.L. Goldin). Reconstitution of Muscle Calcium Channel Function in Bilayer Membranes (D.J. Pelzer et al.). Specific Methods and Tools: Production of Monoclonal Antibodies Against Low Abundance, Ion Channel Associated Proteins in Neuronal Tissue (M. Takahashi). A Highly Porous Sodium DodecylsulfatePolyacrylamide System (J.P. Doucet et al.). Synthesis and Properties of Diazipine, a Novel Photoaffinity Probe for Calcium ChannelLinked DHP Receptors (H. Nakayama et al.). 4 additional articles. Index.