Microarrays in Clinical Diagnostics by Thomas O. JoosMicroarrays in Clinical Diagnostics by Thomas O. Joos

Microarrays in Clinical Diagnostics

byThomas O. Joos

Paperback | November 10, 2010

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Leading academic and industrial investigators surveys the world of microarray technology, describing in step-by-step detail diverse DNA and protein assays in clinical laboratories using state-of-the-art technologies. The advanced tools and methods described are designed for mRNA expression analysis, SNP analysis, identification, and quantification of proteins, and for studies of protein-protein interactions. The protocols follow the successful Methods in Molecular BiologyT series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
Title:Microarrays in Clinical DiagnosticsFormat:PaperbackDimensions:288 pages, 22.9 × 15.2 × 0.01 inPublished:November 10, 2010Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617375381

ISBN - 13:9781617375385

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Table of Contents

Noncontact Laser Microdissection and Pressure Catapulting: Sample Preparation for Genomic, Transcriptomic, and Proteomic AnalysisYilmaz Niyaz, Monika Stich, Bernd Sägmüller, Renate Burgemeister, Gabriele Friedemann, Ulrich Sauer, Rainer Gangnus, and Karin SchützeApplications of the Universal DNA Microarray in Molecular MedicineReyna Favis, Norman P. Gerry, Yu-Wei Cheng, and Francis BaranySensitive Detection of SARS Coronavirus RNA by a Novel Asymmetric Multiplex Nested RT-PCR Amplification Coupled With Oligonucleotide Microarray HybridizationZhi-wei Zhang, Yi-ming Zhou, Yan Zhang, Yong Guo, Sheng-ce Tao, Ze Li, Qiong Zhang, and Jing ChengGenotyping Single-Nucleotide Polymorphisms by Minisequencing Using Tag ArraysLovisa Lovmar and Ann-Christine SyvänenSingle-Nucleotide Polymorphism and Mutation Identification by the Nanogen Microelectronic Chip TechnologyMaurizio Ferrari, Laura Cremonesi, Pierangelo Bonini, Barbara Foglieni, and Stefania StenirriMolecular Diagnostic Testing for Inherited Thrombophilia Using Invader®Margaret A. KellerControlled Agitation During Hybridization: Surface Acoustic Waves Are Shaking Up Microarray TechnologyAchim WixforthRapid Screening for 31 Mutations and Polymorphisms in the Cystic Fibrosis Transmembrane Regulator Gene by Luminex® xMAPT Suspension ArraySherry A. Dunbar and James W. JacobsonProtein Microarray-Based Screening of Antibody SpecificityRhonda Bangham, Gregory A. Michaud, Barry Schweitzer, and Paul F. PredkiMultiplexed Protein Analysis Using Antibody Microarrays and Label-Based DetectionBrian B. HaabAllergen MicroarraysTito Bacarese-Hamilton, Julian Gray, Andrea Ardizzoni, and Andrea CrisantiEnhanced Protein Profiling Arrays for Quantitative Measurement of Protein Expression in Multiple SamplesRuochun Huang, Qian Shi, Weimin Yang, and Ruo-Pan HuangMultiplexed Cytokine Sandwich Immunoassays: Clinical ApplicationsUma Prabhakar, Edward Eirikis, Bruce E. Miller, and Hugh M. DavisValidation and Quality Control of Protein Microarray-Based Analytical MethodsLarry J. Kricka and Stephen R. MasterTissue MicroarraysRonald Simon, Martina Mirlacher, and Guido SauterIndex

Editorial Reviews

From the reviews:"a volume for the specialist with a fascination for the optimal collection and analysis of large data sets in microarray format."-SGM Quarterly"...there is no other comparable book on the market...highly recommended to anyone interested in this rapidly evolving field of technology..." - Doody's Health Science Book Review Journal"Microarray technology has become a mainstay of biological research. . The book is divided into 15 chapters . . Overall this book offers a good read to both clinicians and researchers at the bench who wish to enter the field of microarrays. The format of the book also provides a good roadmap to graduate students wishing to translate aspects of their research to methods amenable to microarrays." (Sridar V. Chittur, Clinical Chemistry, Vol. 52 (6), June, 2006)"Microarrays in Clinical Diagnostics . is a collection of fifteen chapters by authors from both industry and academia, surveying current applications of microarray-based technologies in diagnostics . . provides protocols in the successful style of the Methods in Molecular Biology series, with clarity and sufficient technical detail so that both novice and current microarray users are sure to benefit from this book." (Nicolas Winssinger, ChemMedChem, Issue 1, 2006)