Modeling Neuropsychiatric Disorders In Laboratory Animals by Kurt Leroy HoffmanModeling Neuropsychiatric Disorders In Laboratory Animals by Kurt Leroy Hoffman

Modeling Neuropsychiatric Disorders In Laboratory Animals

byKurt Leroy HoffmanEditorKurt Leroy Hoffman

Hardcover | September 21, 2015

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Modeling Neuropsychiatric Disorders in Laboratory Animalsserves as a guide for students and basic investigators in the fields of behavioral sciences, psychology, neuroscience, psychiatry, and other professionals interested in the use of animal models in preclinical research related to human neuropsychiatric disorders.

The text focuses on the rationale and theory of using animal behavior, both pathological and normal, as a tool for understanding the neural underpinnings of neuropsychiatric disorders. Chapters contain discussions on both classical and modern views on the validation of animal models for neuropsychiatric disorders, also discussing the utility of endophenotypes in modeling neuropsychiatric disease.

Subsequent chapters deal with four specific classes of disorders, including anxiety disorders, depressive disorders, obsessive-compulsive and related disorders. Final sections discuss the future for the development, validation, and use of animal models in basic and preclinical research.



  • Focuses on the rationale and theory of using animal behavior, both pathological and normal, as a tool for understanding the neural underpinnings of neuropsychiatric disorders
  • Serves as a guide for students and basic investigators in the fields of behavioral sciences, psychology, neuroscience, psychiatry, and other professionals
  • Discusses specific classes of disorders, including anxiety disorders, depressive disorders, obsessive-compulsive and related disorders
Dr. Hoffman has studied neurobiological processes in a variety of model animals ranging from Manduca sexta (the common tobacco hawkmoth) to the European rabbit. He received a Bachelor of Science degree in Zoology from the University of Wisconsin, Madison, and a doctoral degree in Biology from the Institute of Neuroscience at the Univer...
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Title:Modeling Neuropsychiatric Disorders In Laboratory AnimalsFormat:HardcoverDimensions:324 pages, 9.41 × 7.24 × 0.98 inPublished:September 21, 2015Publisher:Woodhead PublishingLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0081000995

ISBN - 13:9780081000991

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Table of Contents

  • Chapter 1: What is an animal model, and how is it validated?
  • Chapter 2: Depressive Disorders
  • Chapter 3: Anxiety Disorders
  • Chapter 4: Obsessive-compulsive and related disorders
  • Chapter 5: Synthesis and Future Directions