Molecular And Cellular Therapies For Motor Neuron Diseases by Nicholas M BoulisMolecular And Cellular Therapies For Motor Neuron Diseases by Nicholas M Boulis

Molecular And Cellular Therapies For Motor Neuron Diseases

byNicholas M BoulisEditorDeirdre O Connor, Anthony Donsante

Hardcover | January 18, 2017

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Molecular and Cellular Therapies for Motor Neuron Diseasesdiscusses the basics of the diseases, also covering advances in research and clinical trials. The book provides a resource for students that will help them learn the basics in a detailed manner that is required for scientists and clinicians.

Users will find a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig's Disease) and Spinal Muscular Atrophy (SMA), along with the current understanding of their genetics and mechanisms. In addition, the book details gene and cell therapies that have been developed and their translation to clinical trials.

  • Provides an overview of gene and cell therapies for amyotrophic lateral sclerosis (ALS) and other motor neuron diseases
  • Edited by a leading Neurosurgeon and two research scientists to promote synthesis between basic neuroscience and clinical relevance
  • Presents a great resource for researchers and practitioners in neuroscience, neurology, and gene and cell therapy
Dr. Nicholas Boulis is a physician scientist whose research interests include biological neurorestoration and neuromodulation through the use of cell, protein and gene delivery to the nervous system. Dr. Boulis graduated Summa Cum Laude from Yale University with distinction in intensive Biology and Philosophy majors and graduated Magna...
Title:Molecular And Cellular Therapies For Motor Neuron DiseasesFormat:HardcoverDimensions:336 pages, 9.41 × 7.24 × 0.98 inPublished:January 18, 2017Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0128022574

ISBN - 13:9780128022573

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Table of Contents

Chapter 1. Molecular and Extracellular Cues in Motor Neuron Specification and Differentiation

Chapter 2. Natural History of Amyotrophic Lateral Sclerosis

Chapter 3. Genetics of Amyotrophic Lateral Sclerosis

Chapter 4. Molecular Mechanisms of Amyotrophic Lateral Sclerosis

Chapter 5. An Introduction to the Natural History, Genetic Mapping, and Clinical Spectrum of Spinal Muscular Atrophy

Chapter 6. Genetics of Spinal Muscular Atrophy

Chapter 7. Introduction to Gene and Stem-Cell Therapy

Chapter 8. Gene Therapy for Amyotrophic Lateral Sclerosis: Therapeutic Transgenes

Chapter 9. Stem Cell Therapy for Amyotrophic Lateral Sclerosis

Chapter 10. Gene Therapy for Spinal Muscular Atrophy

Chapter 11. Cellular Therapy for Spinal Muscular Atrophy: Pearls and Pitfalls

Chapter 12. Clinical Trials to Date