Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics

Paperback | July 27, 2016

byLauren Pecorino

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Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers an accessible, engaging, and optimistic account of cancer biology for undergraduate and graduate students. Using the hallmarks of cancer as a starting point, the book looks at the cellular and molecular mechanisms underpinning the transformation of cells into cancer cells. After discussing the theory, each chapter then demonstrates how this knowledge can be directly applied to the development of newtargeted therapies, giving the reader a clear appreciation of how the theory translates to tackling the disease. Drawing on the latest research in this dynamic field, the author makes cutting edge science readily accessible. The book features a variety of learning features - "Pause and think", "How do we know that?", self-tests and activities - to help students engage with, and master, the concepts presented.The emphasis is not on exhaustive coverage of the subject to the point of overwhelming with detail, but on acquiring a solid understanding of the essentials and an appreciation of how a theoretical understanding can be transformed into therapeutic benefit.Online Resource Centre The Online Resource Centre features: For registered adopters of the book: * Figures from the book, ready to download. * A test bank of multiple choice questions, with feedback linked to the book.For students: * Web links to a range of additional cancer biology resources on the internet.

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From the Publisher

Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers an accessible, engaging, and optimistic account of cancer biology for undergraduate and graduate students. Using the hallmarks of cancer as a starting point, the book looks at the cellular and molecular mechanisms underpinning the transformation of cells into can...

Dr Lauren Pecorino obtained her PhD in Cell and Developmental Biology at the State University of New York at Stony Brook, USA. She then moved to London to carry out a post-doctoral tenure at the Ludwig Institute for Cancer Research where she studied the phenomenon of limb regeneration. Here she used a technique called biolistics, using...

other books by Lauren Pecorino

Format:PaperbackDimensions:416 pages, 9.69 × 7.44 × 0.68 inPublished:July 27, 2016Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0198717342

ISBN - 13:9780198717348

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Table of Contents

1. Introduction2. DNA structure and stability: mutations versus repair3. Regulation of gene expression4. Growth factor signaling and oncogenes5. The cell cycle6. Growth inhibition and tumor suppressor genes7. Apoptosis8. Stem cells and consequences of blocked differentiation9. Metastasis10. Angiogenesis11. Nutrients, hormones, and gene interactions12. Tumour immunology and immunotherapy13. Infectious agents and inflammation14. New technologies and drug development

Editorial Reviews

Review of previous edition: "Dr. Pecorino has done a fantastic job... The book's engaging writing-style and well thought out structure welcomes anyone with an interest in studying cancer in thorough, interesting detail. Reading this text was a pleasure, benefited me greatly educationally andmade me feel like being a real part of the teaching - as though things were being explained to me in a one-on-one tutorial, an experience that most other medical textbooks don't provide!" --Amazon.co.uk reviewer