Molecular Epidemiology: Principles and Practices

Paperback | February 6, 1998

byPaul A. SchulteEditorFrederica P. Perera

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This groundbreaking work, now available in paperback, has helped to shape the emerging discipline of molecular epidemiology. Molecular Epidemiology has proven useful to epidemiologists unfamiliar with the terminology and techniques of molecular biology as well as to the molecular biologist working to understand the determinants of human disease and to use that information to control disease. This book demonstrates how molecular epidemiology utilizes the same paradigm as traditional epidemiology in addition to using biological markers to identify exposure, disease, or susceptibility.

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This groundbreaking work, now available in paperback, has helped to shape the emerging discipline of molecular epidemiology. Molecular Epidemiology has proven useful to epidemiologists unfamiliar with the terminology and techniques of molecular biology as well as to the molecular biologist working to understand the determinants of huma...

From the Jacket

This book serves as a primer for laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology builds on the developments and techniques of molecular biology, providing powerful tools to supplement or improve epidemiological research to identify exposure, disease, or susceptibility...

Dr. Schulte is an epidemiologist with interests in education, quantitative risk assessment, health communication, use of biological markers in epidemiologic research, intervention research, and genetics. In recent years, he has conducted extensive research on occupational cancer. He has focused on issues of dissemination of occupationa...

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Format:PaperbackDimensions:588 pages, 9 × 6 × 0.68 inPublished:February 6, 1998Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0126323461

ISBN - 13:9780126323467

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Table of Contents

Contributors.
Preface.
General Principles:
A Conceptual and Historical Framework for Molecular Epidemiology,P.A. Schulte.
Molecular Biology in Epidemiology,R. Hurst and J.Y. Rao.
Validation,P.A. Schulte and F.P. Perera.
Technical Variability in Laboratory Data,P. Vineis, P.A. Schulte, R.F. Vogt, Jr..
Biological Monitoring and Pharmacokinetics Modeling for the Assessment of Exposure,P.O. Droz.
Design Considerations in Molecular Epidemiology,P.A. Schulte, N. Rothman, and D. Schottenfeld.
Statistical Issues and Procedures,V.S. Hertzberg and E. Russek-Cohen.
Biological Specimen Banks: A Resource for Molecular Epidemiologic Studies,D.M. Winn and E.W. Gunter.
Interpretation and Communication of Results,P.A. Schulte.
Use of Biomarkers in Risk Assessment.
Practical Applications,D. Hattis and K. Silver.
Practical Applications:
Carcinogenesis,F.P. Perera and R. Santella.
Infectious Disease,L.H. Harrison and D.E. Griffin.
Cardiovascular Disease,P.A. Schulte, N. Rothman, and M.A. Austin.
Genetic Disease,M.J. Khoury and J.S. Dorman.
Biologic Markers in the Epidemiology of Reproduction,G.K. Lemasters and P.A. Schulte.
Immune Markers in Epidemiologic Field Studies,R.F. Vogt, Jr. and P.A. Schulte.
Biomarkers of Pulmonary Disease,M.S. Tockman, P.K. Gupta, N.J. Pressman and J.L. Mulshine.
Pulmonary Disease.
Biologic Markers in the Genitourinary System,G.P. Hemstreet, III, R.E. Hurst and N.R. Asal.
Neurologic Disease,J.D. Griffith and V.F. Garry.
Practical Applications of Biomarkers in the Study of Environmental Liver Disease,C.H. Tamburro and J.L. Wong.
Biomarkers of Musculoskeletal Disease,J.P. Mastin, G.M. Henningsen, and L.J. Fine.
Epilogue,N. Rothman.
Index.

Editorial Reviews

"This book is an excellent review of the crucial issues related to the incorporation of new markers of exposure, disease, or susceptibility into epidemiologic investigations...This book is an excellent resource for all researchers involved in the quest to understand the determinants of disease and apply this knowledge to the maintenance of the health of the public."
--Science