Molecular Immunology

Paperback | April 30, 1999

EditorB. D. Hames, D. M. Glover

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The book is a collection of up-to-date reviews by major researchers in the field of the fast-moving area of modern immunology. Its wide scope, depth of coverage, well-illustrated text, and the eminence of the authorship make it unique in its field. Over 1900 literature reference are cited.So much has happened in immunology since publication of the first edition of this popular book seven years ago that the second edition is a major new work. The chapters on mechanism and control of immunoglobulin genes by Fred Alt and his colleagues, T-cell antigen receptor genes by Mark Davis andYeuh-hsui Chien, T lymphocyte signal transduction by Cox Terhorst et al, and the complement system by Ken Reid are all major updates and extensions of their first edition contributions. In addition, the second edition contains new chapters by David Jewell and Ian Wilson on the structure andfunction on MHC class I and class II antigens, by John Monaco on molecular mechanisms of antigen processing. By Gerry Klaus on B cell activation, and by Martine Verhoeyen and John Windust in recent advances by antibody engineering.

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The book is a collection of up-to-date reviews by major researchers in the field of the fast-moving area of modern immunology. Its wide scope, depth of coverage, well-illustrated text, and the eminence of the authorship make it unique in its field. Over 1900 literature reference are cited.So much has happened in immunology since publ...

B. David Hames is at University of Leeds. David Glover is at University of Dundee.

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Format:PaperbackDimensions:404 pages, 9.69 × 7.44 × 0.87 inPublished:April 30, 1999Publisher:Oxford University Press

The following ISBNs are associated with this title:

ISBN - 10:0199633789

ISBN - 13:9780199633784

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Table of Contents

1. Rusty Lansford, Ami Okada, Jianzhu Chen, Eugene M. Oltz, T. Keith Blackwell, Frederick W. Alt, and Gary Rathbun: Mechanism and control of immunoglobulin gene rearrangement2. Mark M. Davis and Yueh-hsui Chien: T cell antigen recepotor genes3. Cox Terhorst, Mark Exley, Frank Staal and Hergen Spits: T lymphocyte signal transduction4. David Jewell and Ian A. Wilson: Structure and function of MHC class I and class II antigens5. John J. Monaco: Molecular mechanisms of antigen processing6. Gerry G.B. Klaus: B cell activation7. Martine E. Verhoeyen and John H.C. Windust: Advances in antibody engineering8. Kenneth B.M. Reid: The complement system

Editorial Reviews

"Its chapters are written by leading experts, and the information is presented in a comprehensive yet direct manner. The most striking feature of the book is the number of references cited. Close to 2,000 publications, all with complete titles and authors, are referred to. . . . On the whole, presentations are even and well thought out."--Quarterly Review of Biology"An excellent second edition on important topics in molecular immunology. It covers in detail the generation and application of engineered antibodies and the molecular mechanisms of antigen presentation; immunoglobulin and T cell receptor rearrangements and expression; and the activation of B cells, T cells, and the complement cascade. The book incorporates contributions from recognized experts, most of whom work for academic research institutions in the U.S....Excellent and comprehensive."--Doody's Health Sciences Book ReviewListed in "Books of Interest" in Journal of Medicinal Chemistry