Molecular Mechanisms That Orchestrate The Assembly Of Antigen Receptor Loci by Cornelis Murre

Molecular Mechanisms That Orchestrate The Assembly Of Antigen Receptor Loci

byCornelis MurreEditorCornelis Murre

Hardcover | October 16, 2015

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Molecular Mechanisms That Orchestrate the Assembly of Antigen Receptor Loci, the latest volume in theAdvances in Immunologyseries focuses on the generation of an effective immune response to invading pathogens

As B and T lymphocytes are characterized by the expression of antigen receptors that specifically recognize determinants expressed on pathogens, this volume discusses how antigen receptors are synthesized in B and T lymphocytes.



  • Focuses on the generation of an effective immune response to invading pathogens
  • Contains contributions from leading authorities
  • Informs and updates on all the latest developments in the field of immunology

About The Author

Cornelis Murre performed his graduate work as a joined program with the University of Leiden at Harvard Medical School. He was a postdoctoral fellow at the Whitehead Institute. He is a Searle Scholar and the recipient of the National Institutes of Health Merit Award. Currently he is a Distinguished Professor in the Biological Sciences ...
Epigenetic Regulation of Lymphocyte Development
Epigenetic Regulation of Lymphocyte Development

by Cornelis Murre

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Title:Molecular Mechanisms That Orchestrate The Assembly Of Antigen Receptor LociFormat:HardcoverDimensions:454 pages, 9.41 × 7.24 × 0.98 inPublished:October 16, 2015Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0128032960

ISBN - 13:9780128032961

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Table of Contents

  1. Regulation and Evolution of the RAG Recombinase
    Grace Teng and David G. Schatz
  2. Chromatin Interactions in the Control of Immunoglobulin Heavy Chain Gene Assembly
    Gita Kumari and Ranjan Sen
  3. Spatial Regulation of V-(D)J Recombination at Antigen Receptor Loci
    Anja Ebert, Louisa Hill and Meinrad Busslinger
  4. Long Range Regulation of V(D)J Recombination
    Charlotte Proudhon, Bingtao Hao, Ramya Raviram, Julie Chaumeil and Jane A. Skok
  5. Dynamic Control of Long-range Genomic Interactions at the Immunoglobulin º Light Chain Locus
    Claudia Ribeiro de Almeida, Rudi W. Hendriks and Ralph Stadhouders
  6. Regulation of Tcrb Gene Assembly by Genetic, Epigenetic, and Topological Mechanisms
    Kinjal Majumder, Craig H. Bassing and Eugene M. Oltz
  7. Chromatin Dynamics and the Development of the TCR± and TCRd Repertoires
    Zachary Carico and Michael S. Krangel
  8. Long-range Control of V(D)J Recombination & Allelic Exclusion: Modeling Views
    Pernelle Outters, Sébastien Jaeger, Nancy Zaarour and Pierre Ferrier