Molecular Pathogenesis And Signal Transduction By Helicobacter Pylori by Nicole TegtmeyerMolecular Pathogenesis And Signal Transduction By Helicobacter Pylori by Nicole Tegtmeyer

Molecular Pathogenesis And Signal Transduction By Helicobacter Pylori

byNicole TegtmeyerEditorSteffen Backert

Paperback | July 13, 2018

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This volume reviews the current state of research concerning bacterial virulence factors and the infection biology ofHelicobacter pylori, which is the leading cause of peptic ulcers and gastric cancer worldwide. The chapters include cutting-edge findings on this fascinating microbe and discuss the general strategies ofH. pyloriinfection and persistence, news on importantH. pylorivirulence factors, crosstalk with the microbiota, hot novel models and signaling mechanisms, risk factors of gastric disease and stomach cancer, and the impact ofH. pyloriinfection on non-gastric diseases. Written by internationally respected scientists, this book will appeal to clinicians, researchers and advanced students alike.

Dr. rer. nat. Nicole Tegtmeyer Prof. Dr. rer. nat. Steffen Backert Chair of MicrobiologyFriedrich Alexander University Erlangen/NurembergDepartment of Biology, Division of MicrobiologyStaudtstr. 591058 ErlangenGermany
Title:Molecular Pathogenesis And Signal Transduction By Helicobacter PyloriFormat:PaperbackDimensions:347 pages, 9.41 × 7.24 × 0.98 inPublished:July 13, 2018Publisher:Springer NatureLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3319844180

ISBN - 13:9783319844183


Table of Contents

The human stomach in health and disease: infection strategies byHelicobacter pylori.-Human andHelicobacterpyloriInteractions Determine the Outcome of Gastric Diseases.- Immune evasion strategies and persistence ofHelicobacterpylori.-Recent advances inHelicobacter pylorireplication: possible implications in adaptation to a pathogenic lifestyle and perspectives for drug design.- TheHelicobacterpyloriMethylome: Roles in Gene Regulation and Virulence.- Structural insights intoHelicobacterpyloriCag protein interactions with host cell factors.- Gastric organoids: An emerging model system to studyHelicobacterpyloripathogenesis.- DNA Transfer and Toll-Like Receptor Modulation by Helicobacter pylori.- Exploiting the gastric epithelial barrier:Helicobacter pylori'sattack on tight and adherens junctions.-Helicobacterpylori-induced Changes in Gastric Acid Secretion and Upper Gastrointestinal Disease.- Impact of the microbiota and gastric disease development byHelicobacterpylori.-Pathogenesis of gastric cancer: genetics and molecular classification.-Helicobacterpylori-mediated genetic instability and gastric carcinogenesis.-Helicobacterpyloriand extragastric diseases.