Molecular Signaling and Regulation in Glial Cells: A Key to Remyelination and Functional Repair by Gunnar JeserichMolecular Signaling and Regulation in Glial Cells: A Key to Remyelination and Functional Repair by Gunnar Jeserich

Molecular Signaling and Regulation in Glial Cells: A Key to Remyelination and Functional Repair

EditorGunnar Jeserich, Hans H. Althaus, Christiane Richter-Landsberg

Paperback | September 19, 2011

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An excellent survey of the most recent advances in the area of cellular and molecular biology of glial cells and their involvement in remyelination and functional repair in the CNS. A major part of this book deals with signaling paths within and among neural cells. Glial cells (astrocytes, oligodentrocytes, microglial cells) themselves release substantial amounts of cytokines, growth factors and other signaling molecules, which play an important role during injury and regeneration. Another signaling route between neurons and glial cells follows ion channels and neurotransmitter receptors. In addition to animal models, human oligodentrocytes in cell culture and in the human MS brain are characterized with respect to their immunocytochemistry and function.
Title:Molecular Signaling and Regulation in Glial Cells: A Key to Remyelination and Functional RepairFormat:PaperbackDimensions:406 pagesPublished:September 19, 2011Publisher:Springer Berlin HeidelbergLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3642645011

ISBN - 13:9783642645013

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Table of Contents

Contents: Part 1: Signaling for Glial Cells.- Cytokines, Growth Factors and Their Intracellular Cascades.- Ion Channels and Neurotransmitter Receptors. Part 2: Genes and Proteins of Myelin.- Structure, Regulation and Function. Part 3: Neural Repair Mechanisms in the CNS. Cellular Responses to Injury.- Remyelination of Lesions in Multiple Sclerosis. Cell Transplantation.