Mood and Anxiety Related Phenotypes in Mice: Characterization Using Behavioral Tests by Todd D GouldMood and Anxiety Related Phenotypes in Mice: Characterization Using Behavioral Tests by Todd D Gould

Mood and Anxiety Related Phenotypes in Mice: Characterization Using Behavioral Tests

EditorTodd D Gould

Paperback | March 7, 2012

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Affecting approximately twenty percent of the world population, mood and anxiety disorders have been the subject of ever-increasing research. This increased research parallels a remarkable growth in the use of the laboratory mouse as a tool to understand the biological and genetic basis of mood and anxiety disorders as well as to develop improved treatments. In Mood and Anxiety Related Phenotypes in Mice: Characterization Using Behavioral Tests, world-renowned researchers provide an overview of behavioral approaches utilized in the characterization of mood and anxiety related behaviors in mice as well as commonly used behavioral assays to assess the potential antidepressant and anxiolytic efficacy of novel compounds. As a volume in the successful NeuromethodsT series, the chapters provide authoritative reviews including up-to-date detailed protocols of the most commonly used approaches in the field. Mood and Anxiety Related Phenotypes in Mice: Characterization Using Behavioral Tests is an ideal resource for scientists actively pursuing or interested in establishing behavioral protocols in their laboratories, while also serving as a reference for those students, scientists, and practitioners who have an interest in better understanding the preclinical behavioral methods used in mood and anxiety research.
Title:Mood and Anxiety Related Phenotypes in Mice: Characterization Using Behavioral TestsFormat:PaperbackDimensions:346 pages, 10.24 × 7.6 × 0 inPublished:March 7, 2012Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617796549

ISBN - 13:9781617796548

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Table of Contents

1. The Open Field TestTodd D. Gould, David T. Dao, and Colleen E. Kovacsics2. Analysis of Grooming Behavior and its Utility in Studying Animal Stress, Anxiety, and DepressionAmanda N. Smolinsky, Carisa L. Bergner, Justin L. LaPorte, and Allan V. Kalueff3. Digging in Mice: Marble Burying, Burrowing, and Direct Observation Reveal Changes in Mouse BehaviorRobert M.J. Deacon4. Circadian and Light Modulation of BehaviorCara M. Altimus, Tara A. LeGates, and Samer Hattar5. Ultrasonic Vocalizations by Infant Mice: An Ethological Expression of Separation AnxietyJames T. Winslow6. The Forced Swimming Test in Mice: A Suitable Model to Study AntidepressantsMartine Hascoët and Michel Bourin7. The Tail Suspension Test: A Model for Characterizing Antidepressant Activity in MiceOlivia F. O'Leary and John F. Cryan8. Stress-Induced Hyperthermia in the MouseChristiaan Vinkers, Ruud van Oorschot, Berend Olivier, and Lucianne Groenink9. Factors of Reproducibility of Anhedonia Induction in a Chronic Stress Depression Model in MiceTatyana Strekalova and Harry Steinbusch10. Learned Helplessness in MiceHymie Anisman and Zul Merali11. The Mouse Light-Dark Box TestMartine Hascoët and Michel Bourin12. Using the Elevated Plus Maze as a Bioassay to Assess the Effects of Naturally-Occurring, and Exogenously-Administered Compounds, to Influence Anxiety-Related Behaviors of MiceAlicia A. Walf and Cheryl A. Frye13. Novelty-Induced Hypophagia Stephanie C. Dulawa14. Acute and Chronic Social Defeat: Stress Protocols and Behavioral TestingAlessandro Bartolumucci, Eberhard Fuchs, Jaap M. Koolhaas, and Frauke Ohl15. Reduction of Submissive Behavior Model for Antidepressant Drug Testing in MiceEwa Malatynska, Albert Pinhasov, and Richard J. Knapp16. Mice Models for the Manic Pole of Bipolar Disorder Shlomit Flaisher-Grinberg and Haim Einat

Editorial Reviews

From the reviews:"Part of the Neuromethods Series, this book describes behavioral protocols that are used in laboratory experiments with mice in order to understand mood and anxiety related phenotypes. . This excellent book describes specific behavioral tests in great detail. Readers who have a strong foundation in research will be very pleased because they can replicate the tests with the information here and the protocols are analyzed in terms of their usefulness." (Gary B. Kaniuk, Doody's Review Service, June, 2010)