Mood Genes: Hunting for Origins of Mania and Depression

Paperback | September 15, 1999

bySamuel H. Barondes

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We know that the likelihood of developing many physical diseases, such as diabetes, is determined by genes. But can abnormalities in specific genes also play a part in the development of mental disorders? And, if so, can these genes actually be identified and their discovery put to use inprevention and treatment? In Mood Genes, leading psychiatrist and biological researcher Samuel Barondes answers these questions in a way that renders a complex subject both exciting and understandable. Focusing on manic depressive illness, which affects about one percent of the population and has long been known to run infamilies, Barondes describes the fascinating hunt for genes--called mood genes--that influence the inherited vulnerability to severe mood disorders. He builds the compelling story of this hunt on the histories of two families riddled with manic-depression, explaining what it means to have aninherited predisposition to a severe mood disorder, how to find the mood genes that are responsible, and what will happen as mood genes are found. Not long ago, saying that a behavioral tendency was genetic was generally taken to mean that it was unchangeable. Now we know that finding genes that influence particular behavioral variations may not just be used to foretell our destinies--but also to forestall them.

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One day, your partner can seem like he’s over the moon, but by evening, his could mood plummet so low that it seems like he’s reached the depths of hellLife can be a long, drawn out nightmare for people with manic depressive disorder. And it can be equally as painful for their partners too. In Mood Genes, psychiatrist Samuel H. Baronde...

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We know that the likelihood of developing many physical diseases, such as diabetes, is determined by genes. But can abnormalities in specific genes also play a part in the development of mental disorders? And, if so, can these genes actually be identified and their discovery put to use inprevention and treatment? In Mood Genes, leadin...

Samuel H. Barondes, M.D., is the Jeanne and Sanford Robertson Professor and Director of the Center for Neurobiology and Psychiatry at the University of California, San Francisco. He recently chaired the Workgroup on Genetics of the National Institute of Mental Health, and is the author of Scientific American Library's Molecules and M...

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Format:PaperbackDimensions:256 pages, 7.91 × 5.31 × 0.39 inPublished:September 15, 1999Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0195131061

ISBN - 13:9780195131062

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From Our Editors

One day, your partner can seem like he’s over the moon, but by evening, his could mood plummet so low that it seems like he’s reached the depths of hellLife can be a long, drawn out nightmare for people with manic depressive disorder. And it can be equally as painful for their partners too. In Mood Genes, psychiatrist Samuel H. Barondes sheds some light on this potentially debilitating mental illness and examines the implications of genetic determination research for potentially halting the hereditary genes.

Editorial Reviews

"[A] fascinating detective story....essential for those who want to keep pace with the rapidly evolving sciences that seek to tell us exactly who we are."--The New York Times Book Review