Mouse Models in the Study of Genetic Neurological Disorders

Hardcover | February 28, 1999

EditorBrian Popko

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This volume covers the use of animal models for human genetic disease, including models of developmental disorders, neuromuscular diseases, neurodegenerative diseases and learning disorders. Researchers who study these disorders will find this volume a useful resource.

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This volume covers the use of animal models for human genetic disease, including models of developmental disorders, neuromuscular diseases, neurodegenerative diseases and learning disorders. Researchers who study these disorders will find this volume a useful resource.

Format:HardcoverDimensions:377 pages, 9.25 × 6.1 × 0.27 inPublished:February 28, 1999Publisher:Springer USLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0306459655

ISBN - 13:9780306459658

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Table of Contents

1. An Overview of Mouse Models in Neuroscience Research; B. Popko. 2. X-Linked Dysmyelination: Mouse Models of Pelizaeus-Merzbacher Disease; K.-A. Nave. 3. Charcot-Marie-Tooth Disease: Pathology, Genetics and Animal Models; U. Suter. 4. Mouse Mutations in the Study of Cerebellar Development; D. Karagogeos, O. Pavlou . 5. The Role of Neurotrophic Factors in Development and Neurodegenerative Disorder; W.D. Snider, I. Silos-Santiago. 6. Transgenic Mice with Neurofilament Abnormalities; C. Lampron, et al. 7. Mouse Models of Amyotrophic Lateral Sclerosis; T.L. Williamson, D.W. Cleveland. 8. Transgenic Mouse Models of CAG Trinucleotide Repeat Neurologic Diseases; H.T. Orr, H.Y. Zoghbi. 9. Alzheimer's Disease and Genetically Engineered Animal Models; D.R. Borchelt, et al. 10. Model of Genetic Susceptibility to Late-Onset Alzheimer's Disease: Mice Transgenic for Human Apolipoprotein E Alleles; D.E. Schmechel, et al. 11. Lysosomal Disorders; K. Suzuki, et al. 12. Neurological Implications of the Genetic Mouse Modesl Human Phenylketonuria and Hyperphenylalinemia; J.D. McDonald. 13. Mouse Models of Down Syndrome; M.T. Davisson, A.C. Costa. 14. Modeling Epileptic Disorders in Mice; T.N. Seyfried, et al.