Mucosal Immune Defense: Immunoglobulin A by Charlotte S. KaetzelMucosal Immune Defense: Immunoglobulin A by Charlotte S. Kaetzel

Mucosal Immune Defense: Immunoglobulin A

byCharlotte S. Kaetzel

Paperback | November 4, 2010

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This key work in the field draws on a broad spectrum of molecular biologic, biochemical, and immunogenetic approaches in combination with human and murine in vitro cell culture and in vivo model systems to address questions in mucosal immunity. Humans produce more immunoglobulin A (IgA) than all other antibody isotypes combined. This book is designed to serve as a concise reference of the present knowledge of the biology of IgA.
Dr. Charlotte Kaetzel received her PhD and postdoctoral training in biochemistry and cell biology from the University of Maryland. Her introduction into the world of immunology came with her first faculty appointment in 1983 in the Department of Pathology at Case Western Reserve University in Cleveland. Under the mentorship of departme...
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Title:Mucosal Immune Defense: Immunoglobulin AFormat:PaperbackDimensions:434 pagesPublished:November 4, 2010Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1441944273

ISBN - 13:9781441944276

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Table of Contents

Structure of IgA.- IgA Plasma Cell Development.- Epithelial Transport of IgA by the Polymeric Immunoglobulin Receptor.- Fc Receptors for IgA.- Regulation of the Mucosal IgA System.- Biological Functions of IgA.- Protection of Mucosal Epithelia by IgA: Intracellular Neutralization and Excretion of Antigens.- Novel Functions of Secretory IgA.- IgA and Antigen Sampling.- IgA and Intestinal Homeostasis.- IgA and Respiratory Immunity.- IgA and Reproductive Tract Immunity.- IgA-Associated Diseases.- Mucosal SIgA Enhancement: Development of Safe and Effective Mucosal Adjuvants and Mucosal Antigen Delivery Vehicles.- Recombinant IgA Antibodies.