Multiscale Modeling in Biomechanics and Mechanobiology by Suvranu DeMultiscale Modeling in Biomechanics and Mechanobiology by Suvranu De

Multiscale Modeling in Biomechanics and Mechanobiology

bySuvranu DeEditorWonmuk Hwang, Ellen Kuhl

Hardcover | October 29, 2014

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Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. It develops the reader's understanding of and intuition for multiscale phenomena in biomechanics and mechanobiology, and introduces a mathematical framework and computational techniques paramount to creating predictive multiscale models.

Biomechanics involves the study of the interactions of physical forces with biological systems at all scales - including molecular, cellular, tissue and organ scales. The emerging field of mechanobiology focuses on the way that cells produce and respond to mechanical forces - bridging the science of mechanics with the disciplines of genetics and molecular biology. Linking disparate spatial and temporal scales using computational techniques is emerging as a key concept in investigating some of the complex problems underlying these disciplines.

Providing an invaluable field manual for graduate students and researchers of theoretical and computational modelling in biology, this book is also intended for readers interested in biomedical engineering, applied mechanics and mathematical biology.

Prof Suvranu De serves as Professor and Head of the Department of Mechanical, Aerospace and Nuclear Engineering (MANE) and Director of the Center for Modeling, Simulation and Imaging in Medicine (CeMSIM) at Rensselaer Polytechnic Institute, NY, USA. His research is at the intersection of computational mechanics and the health sciences....
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Title:Multiscale Modeling in Biomechanics and MechanobiologyFormat:HardcoverDimensions:286 pagesPublished:October 29, 2014Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1447165985

ISBN - 13:9781447165989

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Table of Contents

1. Proteins: Ssp DnaE Intein.- 2. Protein Crystals: Molecular to Continuum Level Models based on Crystal Plasticity Theory.- 3. Molecular Motors: Cooperative Phenomena of Multiple Molecular Motors. - 4. Biofilament dynamics: Line-to-rod-level Descriptions.- 5. Primary Cilia: Multi-Scale Structures that integrate Biomechanics and Mechanobiology. - 6. Biological Scaffolding: Reduced-Order Network Models.- 7. Transport phenomena: Computational models for convective and diffusive transport in capillaries and tissue.- 8.Tendons and ligaments: Current state and future directions. - 9. Arteries: Mechanics, Mechanobiology, and the Need for a New Class of Models.- 10. Mitral Valves: A computational framework. - 11. Biological systems: Multiscale modeling based on Mixture Theory.