Nanoparticles And The Immune System: Safety And Effects

Paperback | December 9, 2013

byDiana BoraschiEditorAlbert Duschl

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Nanoparticles and the Immune System provides a reference text for toxicologists, materials scientists and regulators and covers the key issues of interaction of nanomaterials with the immune system. The book discusses several issues that toxicologists and regulators need to know: identification of endpoints that are relevant for assessing hazard, evaluating impact on immunologically frail populations, and how to evaluate chronic/cumulative effects. In addition, the book addresses the possibility of turning the immunomodulating properties of certain nanomaterials to our advantage for amplifying immune responses in certain diseases or preventive strategies e.g. vaccination . Identifies endpoints relevant for assessing hazardous situations, evaluating the impact on immunologically frail populations and how to gauge chronic/cumulative effects Raises the awareness of the importance of knowing the effects of the new nanomaterials on our immune system

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Nanoparticles and the Immune System provides a reference text for toxicologists, materials scientists and regulators and covers the key issues of interaction of nanomaterials with the immune system. The book discusses several issues that toxicologists and regulators need to know: identification of endpoints that are relevant for assess...

Diana Boraschi is an immunologist that built her experience both in academic institutions (Italian National Council for Nuclear Energy, Italian National Research Council, National Cancer Institute in Bethesda, MD, Mario Negri Institute in Milan, Italy, University of Michigan Medical School, Ann Arbor, MI) and industrial settings (the v...

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Format:PaperbackDimensions:138 pages, 9 × 6 × 0.68 inPublished:December 9, 2013Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0124080855

ISBN - 13:9780124080850

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Table of Contents

1. Introduction. How innate and adaptive immunity work
2. Nanoparticles and innate immunity (recognition, reaction/healing vs. chronic inflammation)
3. Nanoparticles and adaptive immunity (T and B cells, antibodies, antigen presentation, autoimmunity)
4. Nanoparticles and allergy/hypersensitivity
5. Nanoparticles and immunological frailty (risk groups)
6. Nanoparticles in medicine
7. Nanoparticles and environmental immunity
8. Summary. Nanoparticle properties vs. immunological mechanisms
9. Conclusions and outlook