Nanotechnology in Drug Delivery

Hardcover | October 27, 2008

EditorMelgardt M. de Villiers

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The reader will be introduced to various aspects of the fundamentals of nanotechnology based drug delivery systems and the application of these systems for the delivery of small molecules, proteins, peptides, oligonucleotides and genes. How these systems overcome challenges offered by biological barriers to drug absorption and drug targeting will also be described.

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 The reader will be introduced to various aspects of the fundamentals of nanotechnology based drug delivery systems and the application of these systems for the delivery of small molecules, proteins, peptides, oligonucleotides and genes. How these systems overcome challenges offered by biological barriers to drug absorption and drug ta...

Format:HardcoverDimensions:676 pages, 10 × 7.01 × 0.04 inPublished:October 27, 2008Publisher:SpringerLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0387776672

ISBN - 13:9780387776675

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Table of Contents

Section 1: Fundamentals of Nanotechnology in Drug Delivery.- Unique Physicochemical Properties of Nanotechnology in Drug Delivery.- PEG Syntheses for Nanotechnology in Drug and Gene Delivery.- Supercritical Fluid Technology for Nanotechnology in Drug Delivery.- Nanotubes, Nanorods, Nanofibers, and Fullerenes for Nanoscale Drug Delivery.- Drug Loading and In Vitro Release Properties of Nanotechnology.- Nanotechnology Based Biosensors in Drug Delivery.- Section 2: Biopharmaceutical, Physiological and Clinical Considerations for Nanotechnology in Drug Delivery.- Nanomaterials and Biocompatibility: Biomems and Dendrimers.- Nanomaterials and Biocompatibility: Carbon Nanotubes and Fullerenes.- Factors Controlling Pharmacokinetics of Intravenously Injected Nanoparticulate Systems.- Controlled Release of Nanotechnology.- Nanotechnology for Intracellular Delivery and Targeting.- Section 3: Nanotechnology for the Delivery of Small Molecules, Peptide, Protein and Nucleic Acids.- Nano-Sized Advanced Delivery Systems as Parenteral Formulation Strategies for Hydrophobic Anti-Cancer Drugs.- Amphiphilic Block Copolymers for Nanoscale Drug Delivery.- PAMAM Dendrimers as Nanoscale Oral Drug Delivery Systems.- Nanoemulsions for Intravenous Drug Delivery.- Nanotechnology for Cancer Chemotherapy.- Nanotechnology for Cancer Vaccine Delivery.- Stimuli-Sensitive Nanotechnology for Drug Delivery.- Section 4: A Look to the Future of Nanotechnology in Drug Delivery.- Nanotechnology in Drug Delivery: Past, Present, and Future.- Nanotechnology in Drug Development and Lifecycle Management.- Regulation of Nanotechnology in Drug Delivery.-