Natural Product Chemistry at a Glance by Stephen P. StanforthNatural Product Chemistry at a Glance by Stephen P. Stanforth

Natural Product Chemistry at a Glance

byStephen P. Stanforth

Paperback | August 11, 2006

Pricing and Purchase Info


Earn 292 plum® points

Prices and offers may vary in store


In stock online

Ships free on orders over $25

Not available in stores


Natural products have been a fertile area of chemical investigation for many years, driving the development of both analytical chemistry and of new synthetic reactions and methodologies. Many of the most important synthetic reactions in chemistry have been developed in the quest to characterise and synthesise these materials.

Natural Product Chemistry at a Glance provides a concise overview of the main principles and reactions of natural product chemistry, for students studying chemistry and related courses at undergraduate level. Based on the highly successful and student friendly "at a glance" approach, the material developed in this book has been chosen to reinforce the principles of elementary organic reactions and to highlight the similarity between many organic reactions and biological processes. It will also serve as an initial platform for more advanced excursions into the origin of natural products.

Students using Natural Product Chemistry at a Glance will find they have a resource with which they can quickly, economically and confidently acquire, regularly review and revise the basic facts that underpin the biosynthesis and chemistry of natural products.
Stephen Stanforth is a Reader in the School of Applied Sciences, Northumbria University, Newcastle upon Tyne, UK.
Title:Natural Product Chemistry at a GlanceFormat:PaperbackDimensions:148 pages, 11.7 × 8.3 × 0.35 inPublished:August 11, 2006Publisher:WileyLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1405145625

ISBN - 13:9781405145626

Look for similar items by category:


Table of Contents

Section 1: Introduction.

1.1 Primary and Secondary Metabolites.

1.2 Properties and Purpose of Secondary Metabolites.

Section 2: Acetyl Coenzyme A: A Key Biological Intermediate.

2.1 What is Acetyl Coenzyme A? 8.

2.2 Comparison of Organic and Acetyl Coenzyme A Reactions.

2.3 Malonyl Coenzyme A – A Partnership with Acetyl Coenzyme A.

2.4 How is Acetyl Coenzyme A Used in Biosynthesis?.

Section 3: Biosynthesis of Fatty Acids.

3.1 What are Fatty Acids?.

3.2 Occurrence and Function of Fatty Acids.

3.3 Biosynthesis of Saturated Straight-Chain Fatty Acids.

3.4 Biosynthesis of Saturated Branched Fatty Acids.

3.5 Mono-unsaturated Fatty Acids.

3.6 Poly-unsaturated Fatty Acid.

3.7 Oxygenated Fatty Acids.

3.8 β-Oxidation.

Section 4: Biosynthesis of Polyketides.

4.1 What are Polyketides?.

4.2 The Chemistry of 1,3-Dicarbonyls: Keto–Enol Tautomerism.

4.3 The Chemistry of 1,3-Dicarbonyls: Condensation Reactions.

4.4 Polyketide Cyclizations: Formation of Unsaturated Products.

4.5 Secondary Structural Modifications During Polyketide Cyclizations.

4.5.1 Alkylation.

4.5.2 Reduction.

4.5.3 Oxidation.

4.5.4 Decarboxylation.

4.5.5 Modifications to the Carbon Skeleton.

4.6 Alkaloids Derived from Polyketides.

4.7 The Use of Isotopes in the Elucidation of Biosynthetic Pathways.

Section 5: The Shikimic Acid Pathway.

5.1 Introduction.

5.2 Transamination.

5.3 Biosynthesis of Natural Products Derived from Cinnamic Acid.

5.4 Lignans.

5.5 Biosynthesis of Alkaloids.

5.5.1 Decarboxylation of Amino Acids and α-Keto Acids.

5.5.2 Pictet–Spengler Reaction.

5.5.3 Alkaloids Derived from Tryptophan.

5.5.4 Alkaloids Derived from Tyrosine.

Section 6: Terpenes.

6.1 What are Terpenes?.

6.2 Carbocations as Intermediates in Terpene Biosynthesis.

6.2.1 Hydride Shifts.

6.2.2 Alkyl Shifts.

6.2.3 Cyclizations.

6.3 Termination of Carbocations.

6.3.1 Loss of a Proton.

6.3.2 Addition of Water.

6.4 Terpene Biosynthesis.

6.4.1 Biosynthesis Initiated by Heterolysis of Pyrophosphates.

6.4.2 Biosynthesis from ‘Dimers’ of Pyrophosphates.

6.4.3 Biosynthesis Initiated by Protonation or Epoxidation of an Alkene.

Section 7: Natural Products Derived from Amino Acids.

7.1 Alkaloids.

7.2 Penicillins and Related Compounds 1.1 Primary and Secondary Metabolites.

7.3 Macrocyclic Peptides.

7.4 Porphyrins.

Section 8: Answers to Problems.

Section 9: Further Reading.


Editorial Reviews

"The author has successfully steered a course that charts the main chemical aspects of natural products and their biosynthesis, without becoming unduly enmeshed in biological aspects of the subject, and this is a strategy that will very well suit the target audience....The book is well balanced in its coverage, sensibly treating the fuzzy boundary between primary and seconday metabolism....this is a valuable addition to the 'at a glance' stable, and will find a welcome home in undergraduate chemistry curricula in the UK and abroad."Chemistry World"The undergraduate student who wants to know the mechanistic chemistry of biosynthesis is well served by this book."Education in Chemistry