Neural Mechanisms of Anesthesia by Joseph E. AntogniniNeural Mechanisms of Anesthesia by Joseph E. Antognini

Neural Mechanisms of Anesthesia

EditorJoseph E. Antognini

Paperback | November 9, 2010

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Leading investigators critically evaluate the latest information on how anesthetics work at the molecular, cellular, organ, and whole animal level. These distinguished experts review anesthetic effects on memory, consciousness, and movement and spell out in detail both the anatomic structures and physiological processes that are their likely targets, as well as the cellular and molecular mechanisms by which they operate. Comprehensive and authoritative, Neural Mechanisms of Anesthesia draws together and critically reviews all the recent research on anesthetic mechanisms, highlighting the precise routes along which these substances operate, and how this deeper understanding will lead to the design of effective drugs free ofundesirable side effects.
Title:Neural Mechanisms of AnesthesiaFormat:PaperbackDimensions:478 pages, 10 × 7.01 × 0 inPublished:November 9, 2010Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617372943

ISBN - 13:9781617372940

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Table of Contents

I. IntroductionThe Development of Concepts of Mechanisms of AnesthesiaDonald Caton and Joseph F. AntogniniII. Anesthesia, Consciousness, and MemoryMechanisms of Consciousness with Emphasis on the Cerebral Cortical ComponentG. Bryan YoungAnesthesia Meets Memory: Tools for Critical AppraisalRobert A. VeselisIII. Sleep, Coma, and Anesthesia-Similarities and DifferencesSleep and AnesthesiaJohn KeiferPossible Relationships of Anesthetic Coma and Pathological Disorders of ConsciousnessNicholas D. Schiff and Fred PlumIV. Neural MechanismsCerebral Cortex-Anesthetic Action on the Electroencephalogram: Cellular and Synaptic Mechanisms and Clinical MonitoringHeath Lukatch and Scott GreenwaldCerebral Mechanisms of Analgesia and Anesthesia in Humans Elucidated by In Vivo Brain ImagingFerenc Gyulai and Leonard FirestoneThalamusAnthony AngelThe HippocampusM. Bruce MacIverAnesthetic Effects on the Reticular Formation, Brainstem and Central Nervous System ArousalJoseph F. Antognini and Earl CarstensAnesthesia, the Spinal Cord and Motor Responses to Noxious StimulationJoseph F. Antognini and Earl CarstensSpinal Cord-Dorsal HornJ. G. CollinsSpinal Cord: Anesthetic Actions on Motor NeuronsJoan J. KendigSimple Genetic Models for Anesthetic ActionPhilip G. Morgan and Margaret SedenskyGenetic Dissection of Anesthetic ActionGregg E. Homanics and Leonard L. FirestoneV. Cellular and Molecular MechanismsGeneral Anesthetic Effects on GABAA ReceptorsRobert A. PearceNicotinic Acetylcholine Receptors and AnestheticsStuart A. Forman, Pamela Flood, and Douglas RainesActions of General Anesthetic on Voltage-Gated Ion ChannelsNorbert Topf, Esperanza Recio-Pinto, Thomas J. J. Blanck, and Hugh C. Hemmings, JrGlutamate Receptors: Physiology and Anesthetic PharmacologyMisha Perouansky and Joseph F. AntogniniGeneral Anesthetic Effects on Glycine ReceptorsStephen DanielsPresynaptic Actions of General AnestheticsMisha Perouansky and Hugh C. Hemmings, JrThe Meyer-Overton Relationship and Its ExceptionsWarren S. Sandberg and Keith W. MillerProtein ModelsJonas S. Johansson and Roderic G. EckenhoffThe Opioid ReceptorsGary J. Brenner, Jianren Mao, and Carl RosowLocal AnestheticsGing Kuo WangNeuromuscular Blocking Agents and General AnesthesiaGerald A. Gronert and Timothy TautzVI. Future ResearchThe Future of Anesthetic Mechanisms ResearchJoseph F. Antognini, Douglas E. Raines, and Earl CarstensIndex

Editorial Reviews

"The major strength of this work is that it covers all levels of analysis from observations in behaving humans or animals to studies of molecular and physiochemical phenomena. This provides an excellent opportunity to attenuate the traditional boundaries between molecular and systems level research." -Neural Mechanisms of Anesthesia