Neural Transplantation Methods by Stephen B. DunnettNeural Transplantation Methods by Stephen B. Dunnett

Neural Transplantation Methods

EditorStephen B. Dunnett

Paperback | October 8, 2011

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Leading experimental neurobiologists and neurosurgeons provide all the technical and practical information required to perform neural transplantation in experimental and neurological research, including a detailed consideration of the issues involved in designing and customizing such methods for specific research purposes. The authors outline the different sources of donor tissues and other materials for implantation, review the different techniques for tissue implantation into the brains of experimental animals of different species, and detail the major factors for promoting graft survival, integration, and function. All the techniques are presented in a proven format, along with alternative methods for special experimental needs. Neural Transplantation Methods constitutes the single most comprehensive sourcebook of practical information on the effective use of transplantation techniques in experimental neurobiology. Its powerful and flexible techniques will significantly aid all those now working to develop today's powerful new treatments of brain and spinal cord diseases and injuries.
Title:Neural Transplantation MethodsFormat:PaperbackDimensions:572 pagesPublished:October 8, 2011Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617371912

ISBN - 13:9781617371912

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Table of Contents

Sources of Cells for Transplantation. Dissecting Embryonic Neural Tissues for Transplantation, Stephen B. Dunnett and Anders Björklund. Pregraft Tissue Storage Methods for Intracerebral Transplantation, Hansjörg Sauer. Neural Stem Cells for Transplantation, Siddharthan Chandran and Clive N. Svendsen. Immortalized Cells, Vincent M. Mann and John D. Sinden. Cells from Testis for Transplantation in the CNS, Alison E. Willing and Paul R. Sanberg. Engineered Cells and Ex Vivo Gene Transfer, Cecilia Lundberg. Intracerebral Gene Transfer Using Viral Vectors, Ronald J. Mandel, Steve Hardy, Richard O. Snyder, Luigi Naldini, and Stuart E. Leff. Methods of Implantation. Basic Transplantation Methods in Rodent Brain, Stephen B. Dunnett and Anders Björklund. Intraocular Grafting, Ingrid Strömberg. Neural Transplantation in the Developing CNS, Anthony J. Castro and Jens Zimmer. Preparation of Cell Suspensions for Transplantation, Roger A. Barker, Anne E. Rosser, and Stephen B. Dunnett. Microtransplantation of Nigral Dopamine Neurons: A Step-By-Step Recipe, Guido Nikkhah, Christian Winkler, Alexandra Rödter, and Madjid Samii. Application of Polymer-Encapsulated Cell Therapy for CNS Diseases, Dwaine F. Emerich and Shelley R. Winn. Neural Transplantation in Parkinsonian Primates, Lucy E. Annett. Transplanting Myelinogenic Cells into the CNS, Robin J. M. Franklin and William F. Blakemore. Labeling and Identifying Grafted Cells, Alan R. Harvey. Factors in Graft Survival and Function. Neovascularization and the Blood-Brain Barrier in Neural Transplantation, Jeffrey M. Rosenstein. Trophic Influences on Neural Tissue Transplants: Delivery Methods and Co-graft Interaction, Ann-Charlotte Granholm. Neuroprotective Strategies in Neural Grafting, Patrik Brundin and Gabriele S. Kaminski Schierle. Death and Survival in CNS Grafting, James W. Fawcett. Immunology: Mechanisms of Rejection, Yoshinori Ohmoto and Kathryn Wood. Immunoprotection of Cell and Tissue Implants in the CNS, Colin Watts and Stephen B. Dunnett. Immunobiology of Neural Xenotransplantation, Walter C. Low, Wei-Ming Duan, C. Dirk Keene, Hsiao-Tzu Ni, and Marcus A. Westerman. Index.

Editorial Reviews

"...a book with so much information is very valuable for neuroscientists."- Clinical Neurology and Neurosurgery"Neural Transplantation Methods seeks to serve a particular need: to provide experimental neuroscientists with a source book of information to enable them to select and adapt transplantation techniques to their own experimental programs....Neural Transplantation Methods is a very interesting, up-to-date, and complete book on the technical and methodological issues in relation with experimental neural transplantation. It is a perfect source book of information for those who want to include the transplantation strategy in their experimental program." - Acta Neurologica Belgica